Alumni

Predoctoral Fellows (2020-2021)

Jemar Bather
Academic Advisor: Paige Williams
Jemar is a third year PhD student in the Department of Biostatistics. Jemar’s current research interest is developing a more efficient and unbiased statistical methods for addressing critical questions in evaluating adverse birth outcomes in mothers with HIV. He is currently working on a project to assess the relationship between the empirical power of the inverse probability weighted GEE multiple informant model and the correlation between binary exposures when data is informatively missing. Jemar has conducted simulation studies and a thorough literature review, and will present the results along with his next project at his oral examination in March 2021.

Christina Fennell
Academic Advisor: Dr. Roger Shapiro
Christina is a second year PhD student in the Department of Epidemiology. Christina’s current research interest focuses on exploring barriers to accessing HIV care among marginalized populations. Her current research focuses on evaluating the impact of a recent policy expansion in Botswana, where non-citizens have access to free HIV treatment, among pregnant women. The project seeks to determine the impact of this policy expansion on uptake of government ART among non-citizen, pregnant women and on adverse birth outcomes. Christina is currently developing an analysis plan for this project which will include a descriptive analysis, an interrupted time series analysis, and an exploration of potential risk factors of adverse birth outcomes comparing citizen vs. non-citizen pregnant women. Christina also completed a project that sought to determine the impact of vaginal discharge syndrome and antibiotic use on adverse birth outcomes in Botswana. The project also explored if these associations varied by HIV status.

Linda Harrison
Academic Advisor: Rui Wang
Linda is a fourth year PhD student in the Department of Biostatistics. Linda’s research interests are power calculations for infectious disease clinical trials. Her current research looks at how stepped wedge cluster randomized trials (SW-CRTs), in which an intervention is rolled out sequentially to clusters of individuals, are ideal for pragmatic evaluation of infectious disease control. Existing methods for power calculation when designing a SW-CRT assume the cluster sizes are equal, which may lead to an underpowered study. Linda’s first paper proposes a method to calculate the minimum, maximum and average power of a SW-CRT with variable cluster sizes. Her second planned manuscript addresses power calculation for SW-CRTs when outcomes are binary. In clinical trials there are often missing outcome data. Standard approaches inflate the sample size as if outcome data are missing completely at random and a complete-case analysis will be conducted. Linda’s third paper addresses power calculation in clinical trials when outcome data are missing at random given fully observed covariates.

Jonathan Larson
Academic Advisor: Jukka-Pekka Onnela
Jonathan is a fifth year PhD student in the Department of Biostatistics. His research interests are statistical methods for network data. Jonathan’s first project proposes an affiliation network model of HIV transmission in men who have sex with men and evaluates an estimator of risk based on that model. His second project investigates what we can infer about the minimum spanning tree (MST) of a population graph based on the MST of a sample. And Jonathan’s third project compares different methods of estimating the parameters of the duplication-mutation-complementation (DMC) model of network evolution.

Lara Maleyeff
Academic Advisor: Dr. Rui Wang
Lara is a second year PhD student in the Department of Biostatistics. Her research interest is treatment effect heterogeneity in stepped wedge cluster randomized trials. Lara is currently working on her first paper which explores new modelling and testing frameworks for treatment effect heterogeneity in stepped wedge cluster randomized trials. These trials involve unidirectional cross-over to treatment, with time to cross-over randomized. Existing methodology to account for unknown patterns of exposure time heterogeneity have poor statistical properties. This work proposes a new model and testing framework. This work was submitted in an F31 grant last fall and for the Thomas C. Chalmers Student Scholarship for the Society of Clinical Trials 2021 conference.

Octavious Talbot
Academic Advisor: Jukka-Pekka Onnela
Octavious is a fifth year PhD student in the Department of Biostatistics. His research interests are around detecting homophily within network structures, and determining what factors influences relationship building in a social network. In his paper 1, he created a visual tool that can be used in exploratory data analysis to inspect for homophily in a network. In his paper 2, he is interested in using this tool but also doing further analytical inspection to determine what factors influence relationships being formed in an HIV network. In the network, genetic sequencing is done to infer connections.

Maxwell Wang
Mentor(s): Drs Molin Wang & Rui Wang
Max is a first year PhD student in the Department of Biostatistics. His research interest at this time is modeling of infectious disease transmission and the evaluation of public health interventions. His main focus at this time is on his coursework.

Stephanie Wu
Mentor(s): Drs. Bethany Hedt-Gauthier and Michael Hughes
Stephanie is a second year PhD student in the Department of Biostatistics. She has recently passed the department’s written qualifying exam. Her research interests center on outcome-dependent sampling for correlated binary outcomes, and survey sampling methodology for acquired HIV drug resistance. Stephanie is currently working on a project that looks at outcomedependent sampling for correlated binary outcomes to develop an efficient case-control study design nested within the PHOENIx trial, which is a cluster-randomized prevention trial comparing the efficacy of delamanid to isoniazid for prevention of active tuberculosis among high-risk household contacts of adults with multidrug-resistant tuberculosis. Research is currently ongoing and involves a numerical analysis and simulation study of possible study designs. Stephanie is also working on a project that aims to develop the statistical methods and tools for the WHO’s protocol on laboratory-based surveys of acquired HIV drug resistance using remnant viral load specimens. Acquired drug resistance to dolutegravir-based antiretroviral therapy is a particular focus of the survey, as is the usage of expanded availability of laboratory data in countries. The protocol has been copy-edited and is currently undergoing layout revisions.

Daniel Xu
Mentor(s): Dr. Michael Hughes
Daniel is a first year PhD student in the Department of Biostatistics. Daniel is interested in conducting research that ties together EHR data and clinical trials, and will begin work on an independent study project with Dr. Tianxi Cai this semester.

Postdoctoral Fellows (2020-2021)

Meredith Regan
Mentor(s): Dr. Christopher Sudfeld
Dr. Regan’s research focuses on the intersection of HIV and mental health in resource-limited settings, with the aim of informing interventions and policy. Specifically, she is interested in the ways in which mental health and social determinants of health affect adherence and access to HIV care. She is currently writing up a study based on data from the Familia Salama cluster randomized trial in Dar-es-Salaam, Tanzania. Dr. Regan’s analysis evaluates the impact of a community health worker intervention on frequency and timing of ANC visits and looks at various potential effect modifiers including HIV diagnosis. Having an ANC visit in the first trimester is particularly important for women living with HIV so that they can access prevention of mother-to-child HIV transmission services and initiate antiretroviral treatment if they are not already receiving it. Dr. Regan is also analyzing data from the Trial of Vitamin 5 (ToV5) trial, a cohort of pregnant women living with HIV. She is looking at the association between depression at baseline and birth outcomes, child health outcomes, and early childhood development outcomes. She is also interested in exploring the role of timing of ART initiation as about half the women in the cohort initiated ART at the beginning of the study. Finally, Dr. Regan is very interested in exploring questions around racial, geographic, and socioeconomic disparities in HIV outcomes in the US. She is particularly interested in how COVID-19 has affected access to HIV treatment, and has been doing background reading on this topic in order to formulate a research question and analysis plan. 

Predoctoral Fellows (2018-2019)

Jemar Bather
Academic Advisor: Marcello Pagano
Jemar is a first year PhD student in the Department of Biostatistics. His current focus is completing his coursework.

Linda Harrison
Academic advisor: Marcello Pagano
Linda is a second year PhD student in the Department of Biostatistics.  Her research with Dr. Rui Wang focuses on methods for sample size calculation in stepped wedge cluster randomized trials with variable cluster sizes.

Lee Kennedy-Shaffer
Academic advisor: Michael D. Hughes
Lee is a third-year PhD student in the Department of Biostatistics. His primary research focuses on methods for sample size estimation for cluster randomized trials (CRTs). In particular, he has focused on sample size estimation for stratified CRTs with binary outcomes in infectious disease settings and in what situations stratification can lead to reductions in sample size that have practical relevance to trial design. Included in this research is a deeper understanding of the role of the intracluster correlation coefficient (ICC) for binary outcomes and how the ICC is affected by stratification. Additional research, conducted with Professors Victor De Gruttola and Marc Lipsitch, focuses on methods for vaccine evaluation using novel trial designs and causal inference principles and methods.

Jonathan Larson
Academic Advisor: Jukka-Pekka Onnela
Jonathan is a third-year PhD student in the Department of Biostatistics. His research focuses on random graphs, particularly in the form of HIV transmission networks. Currently, he is developing a model of HIV transmission in men who have sex with men (MSM) based on information about where MSM meet sex partners. This model leads to a natural estimator of risk of infection. Jonathan is also interested in methods for sampling network data as well as methods for predicting characteristics of missing portions of networks.

Gabriel Loewinger
Academic advisor: Michael Hughes
Gabe is a second year PhD student in the Department of Biostatistics. His current focus is completing his coursework.

Mary Kate (MK) Quinn
Academic Advisor: Christopher Sudfeld
MK is a third-year PhD student in the Global Health and Population Department in Population Health Sciences. Her current research is focused on the mechanisms through which different micronutrient exposures affect pregnancy outcomes among women in Tanzania and Ghana. She is also investigating how the timing of ARV initiation during pregnancy affect fetal loss and birth outcomes among women in Tanzania living with HIV.

Dustin Rabideau
Academic Advisor: Rui Wang
Dustin is a third-year PhD student in the Department of Biostatistics. His research interests are broad but currently focus on robust methods for correlated data. Specifically, he is working on permutation methods (i.e. randomization inference) for cluster randomized trials. This general approach provides valid inference even with a small number of clusters, correlated clusters, and when the correlation structure is misspecified. Dustin has also worked with Dr. Judith Lok on inverse probability of censoring weighting when data are missing not at random.

Postdoctoral Fellows (2017-2018)

Elysia Larson
Elysia is a postdoctoral fellow in the Biostatistics department. She works at the intersection of communities and the health system, to measure how patient preferences and facility quality can and do interact to produce better quality of care and better health. Dr. Larson has been the PI, project manager, or statistician for multiple cluster-randomized evaluations of interventions that aim to improve quality of care and health for pregnant women and children living in regions with high HIV-prevalence.

Alex Ocampo (2014 -2020)
Current Position: Principal Statistician, Novartis

Isabel Fulcher (2014-2019)
Current Position: Postdoctoral Fellow, Harvard Data Science Initiative

Jaffer Zaidi (2014-2019)
Current Position: SAMSI Causal Inference Program

Alexander Radunsky (2013-2018)
Current Position: SD student in the Department of Global Health and PopulationAlex’s current research examines a different dimension of cultural norms to understand how HIV manifests in that context. Alex’s three research projects/dissertation papers utilize data from one of three studies in sub-Saharan Africa. In the first, he is using longitudinal demographic and surveillance data from the Africa Centre (K-Rith) in KwaZulu-Natal South Africa to examine HIV incident risk associated with local engagement and marriage patterns in this Zulu community. This work was successfully presented at IAS 2016 as a poster. Completion of this manuscript and submission for publication is scheduled for 2017. In the second project he is using qualitative data from Malawi to examine men’s perceptions of health systems institutions, and attempting to understand in what ways these perceptions influence low HIV testing rates for men in Malawi. I have completed literature review for this paper, the data collection was completed by GAIA in 2015 and analysis and writing for this paper will take place in 2017. In the third he is using qualitative interviews with commercial sex workers in Zambia to will RPPR Page 30
B.4 (B.4 COMBINED AIDS 2017 FINAL.pdf) examine the role that HIV self-testing and the associated improvements in HIV status will play on the price of condomed and condomless sex in this market. This data is being collected by ZEST in collaboration with local partners. Literature review has taken place, data collection is ongoing, and analysis and writing will take place in 2017.

Emily Marie Slade (2013-2018)
Current Position: Assistant Professor, University of Kentucky, Department of Biostatistics, Lexington, KY

Sheila Marie Gaynor (2013-2018)
Current Position: Research Fellow, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA

Katherine Correia (2013-2018)
Current Position: Assistant Professor of Statistics, Amherst College, Mathematics and Statistics Department, Amherst, MA

Isabel Fulcher (2013-2018)
Current Position: PhD Student
Isabel is interested in developing statistical methods that can identify underlying causal mechanisms of potential interventions in settings where this proves particularly challenging, such as in the presence of unmeasured confounding in observational studies and spillover effects on a network. Her primary focus area for application of these methods is sexual and reproductive health, specifically related to HIV treatment and prevention, improvement of maternal health outcomes, and increasing access to family planning. She is also invested in research capacity building in Sub-Saharan Africa. 

Publications while in training include: 

• Fulcher, Isabel R., Tchetgen Tchetgen, E. J., & Williams, P. L. (2017). Mediation Analysis for Censored Survival Data Under an Accelerated Failure Time Model. Epidemiology, 28(5), 660-666.

Kaitlyn Cook (2013-2018)
Current Position: PhD Student
Kaitlyn is a fourth year PhD student in the Department of Biostatistics, where she works to develop statistical methodology for the monitoring and analysis of cluster-randomized trials with interval-censored time-to-event endpoints.  Her research is predominantly motivated by statistical challenges encountered during the Botswana Combination Prevention Project (BCPP), a cluster-randomized trial of combination HIV prevention.  In particular, she has proposed a simulation-based framework to permit conditional power calculation with correlated interval-censored data, and is currently working on bootstrapping and augmentation methods to improve efficiency in cluster-randomized settings. On the basis of her conditional power work, Kaitlyn was named a finalist in the Society for Clinical Trial’s Thomas C. Chalmers Student Scholarship competition, and has been awarded an NRSA individual predoctoral fellowship (F31) to study “Novel Statistical Methods for Cluster-Randomized HIV Prevention Trials.” Kaitlyn is also broadly interested in issues of health equity and LGBTQ healthcare, and is passionate about statistical education and promoting diversity in STEM.

Jessica Lynn Gronsbell (2013-2017)
Current Position: Research Fellow, Stanford University, Biomedical Data Science, Stanford, CA

Evelyn Zheng (2013-2017)
Current Position: Research Associate, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA

Heather Mattie (2011-2017)
Current Position: Executive Director, Master’s Program in Health Data Science
Instructor of Data Science, Department of Biostatistics
Harvard T.H. Chan School of Public Health

Katherine Evans (2012-2017)
Current Position: Quantitative Analyst, Verily Life Sciences, Cambridge, MA

Sarah Anoke (2012-2018)
Current Position: Yerby Research Fellow, Harvard T.H. Chan School of Public Health, Department of Biostatistics, Boston, MA

Emily Rose Smith (2012-2016)
Current Position: Postdoctoral Fellow, Boston Children’s Hospital

Publications while in training include:

• Bahl R, Bhandari N, Dube B, Edmond K, Fawzi W, Fontaine O, Kaur J, Kirkwood BR, Martines J, Masanja H, Mazumder S, Msham S, Newton S, Oleary M, Ruben J, Shannon C, Smith E, Taneja S and Yoshida S. Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial. Trials. 2012 Feb 23;13:22. PMCID: PMC3337818
• Honorati Masanja, Emily RSmith, Alfa Muhihi, Christina Briegleb, Salum Mshamu, Julia Ruben, Ramadhani Abdallah, Noor, Polyna Khudyakov, Sachiyo Yoshida, Jose Martines, Rajiv Bahl, Wafaie W Fawzi. “Effect of neonatal vitamin A supplementation on mortality in infants in Tanzania: a randomized, double-blind, placebo- controlled trial.” Lancet. 2014 Dec 10. PMID: 25499543
• Burke RM, Smith ER, Dahl RM, Rebolledo PA, Calderón Mdel C, Cañipa B, Chavez E, Pinto R, Tamayo L, Terán C, Veizaga A, Zumaran R, Iñiguez V, Leon JS. “The economic burden of pediatric gastroenteritis
  to Bolivian families: a cross-sectional study of correlates of catastrophic cost and overall cost burden.” BMC Public Health. 2014 Jun 24;14:642. PMID: 24962128

Patrick Staples (2011-2016)
Current Position: Data Scientist, Mindstrong, Palo Alto, CA

Yared Gurmu (2011-2016)
Current Position: Lead Biostatistician, Brigham & Women’s Hospital, TIMI Study Group

Publications while in training include:

• Friedman KG, Salvin JW, Wypij D, Gurmu Y, Bacha EA, Brown DW, Laussen PC and Scheurer MA. Risk factors for failed staged palliation after bidirectional Glenn in infants who have undergone stage one palliation. Eur J Cardiothorac Surg. 2011 Oct;40(4):1000-6. PMCID: PMC3376531

Elizabeth Smoot Malecha (2010-2015)
Current Position: Senior Biostatistician, Intercept Pharmaceuticals, Inc.

Publications while in training include: 

• Kennealey PT, Elias N, Hertl M, Ko DS, Saidi RF, Markmann JF, Smoot EE, Schoenfeld DA and Kawai T. A prospective, randomized comparison of bovine carotid artery and expanded polytetrafluoroethylene for permanent hemodialysis vascular access. J Vasc Surg. 2011 Jun;53(6):1640-8. (not federally supported)
• Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J and Uyeki TM. Critically ill children during the 2009-2010 influenza pandemic in the United States. Pediatrics. 2011 Dec;128(6):e1450-8. PMCID: PMC3387899
• van Blitterswijk M, Gulati S, Smoot E, Jaffa M, Maher N, Hyman BT, Ivinson AJ, Scherzer CR, Schoenfeld DA, Cudkowicz ME, Brown RH, Jr. and Bosco DA. Anti-superoxide dismutase antibodies are associated with survival in patients with sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2011 Nov;12(6):430-8. PMCID: PMC3446817
• Yeh H, Smoot E, Schoenfeld DA and Markmann JF. Geographic inequity in access to livers for transplantation. Transplantation. 2011 Feb 27;91(4):479-86. PMCID: PMC3772346
• Rice TW, Rubinson L, Uyeki TM, Vaughn FL, John BB, Miller RR, 3rd, Higgs E, Randolph AG, Smoot EEand Thompson BT. Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States. Crit Care Med. 2012 May;40(5):1487-98. PMCID: PMC3653183

Caleb Miles (2010-2015)
Current Position: Research Fellow, University of California-Berkeley, Computational Biology & Causality, Berkeley, CA

Denis Agniel (2010-2014)
Current Position: Associate Statistician, RAND Corporation, Santa Monica, CA

Publications while in training include:

• Adeyemi OM, Agniel D, French AL, Tien PC, Weber K, Glesby MJ, Villacres MC, Sharma A, Merenstein D, Golub ET, Meyer W and Cohen M. Vitamin D deficiency in HIV-infected and HIV-uninfected women in the United States. J Acquir Immune Defic Syndr. 2011 Jul 1;57(3):197-204. PMCID: PMC3431159
• French AL, Adeyemi OM, Agniel DM, Evans CT, Yin MT, Anastos K and Cohen MH. The association of HIV status with bacterial vaginosis and vitamin D in the United States. J Womens Health (Larchmt). 2011 Oct;20(10):1497-503. PMCID: PMC3233211
• Massad LS, Agniel D, Minkoff H, Watts DH, D’Souza G, Levine AM, Darragh TM, Young M, Cajigas A and Weber K. Effect of stress and depression on the frequency of squamous intraepithelial lesions. J Low Genit Tract Dis. 2011 Jan;15(1):42-7. PMCID: PMC3084664
• French AL, Evans CT, Agniel DM, Cohen MH, Peters M, Landay AL and Desai SN. Microbial translocation and liver disease progression in women coinfected with HIV and hepatitis C virus. J Infect Dis. 2013 Aug 15;208(4):679-89. PMCID: PMC3719907 [Available on 2014/8/15]

Rebecca Payne (2009-2011)
Current Position: Senior Data Scientist, Capital One Auto Finance

Publications while in training include:

• Payne R, Zheng Y, Smoller S, Cai T. Robust Risk Prediction Using Biomarkers from Case Cohort Studies. 2012. [Abstract]
• Payne R, Cai T. Risk Prediction Under Case Cohort Sampling. 2012. [Abstract]

Shira Mitchell (2009-2014)
Current Position: Statistician, Mathematica Policy Research

Publications while in training include:

• Hedt-Gauthier BL, Tenthani L, Mitchell S, Chimbwandira FM, Makombe S, Chirwa Z, Schouten EJ, Pagano M and Jahn A. Improving data quality and supervision of antiretroviral therapy sites in Malawi: an application of Lot Quality Assurance Sampling. BMC Health Serv Res. 2012;12:196. PMCID: PMC3411464
• Mitchell Sand Pagano M. Pooled testing for effective estimation of the prevalence of Schistosoma mansoni. Am J Trop Med Hyg. 2012 Nov;87(5):850-61. PMCID: PMC3516260
• Mitchell SAand Pagano M. Effective classification of the prevalence of Schistosoma mansoni. Trop Med Int Health. 2012 Oct 29. PMCID: PMC3825842
• Mitchell S, Ozonoff A, Zaslavsky AM, Hedt-Gauthier B, Lum K, and Coull BA. Population size estimation with inactive lists: Hierarchical mixture models and missing data with application to armed conflict data. Submitted to the Annals of Applied Statistics
• Mitchell S, Laird L, Pagano M. Nonparametric empirical bayses estimation using an instrument with variable sensitivity: An example with schistosoma mansoni. Submitted to the Annals of Applied Statistics, 2013.
• Mitchell S, Blitzstein J, and Zaslavsky AM. Design-consistency of small area estimators from multilevel regression. Working Paper, 2014

Natalie Exner Dean (2009-2014)
Current Position: Assistant Professor, Department of Biostatistics, University of Florida

Publications while in training include:

• Galler JR, Bryce CP, Zichlin ML, Waber DP, Exner N, Fitzmaurice GM and Costa PT. Malnutrition in the first year of life and personality at age 40. J Child Psychol Psychiatry. 2013 Aug;54(8):911-9. PMCID: PMC3686988 [Available on 2014/8/1]

Christopher Sudfeld (2009-2013)
Current Position: Assistant Professor, Department of Global Health and Population, Harvard T. H. Chan School of Public Health

Publications while in training include:

• Lahariya C, Sudfeld CR, Lahariya D and Tomar SS. Causes of child deaths in India, 1985-2008: a systematic review of literature. Indian J Pediatr. 2010 Nov;77(11):1303-11 (review).
• Sudfeld CR, Navar AM and Halsey NA. Effectiveness of measles vaccination and vitamin A treatment. Int J Epidemiol. 2010 Apr;39 Suppl 1:i48-55. PMCID: PMC2845860
• Imdad A, Yakoob MY, Sudfeld C, Haider BA, Black RE and Bhutta ZA. Impact of vitamin A supplementation on infant and childhood mortality. BMC Public Health. 2011;11 Suppl 3:S20. PMCID: PMC3231894
• Sudfeld CR, Fawzi WW and Lahariya C. Peer support and exclusive breastfeeding duration in low and middle- income countries: a systematic review and meta-analysis. PLoS One. 2012;7(9):e45143. PMCID: PMC3445598
• Sudfeld CR, Wang M, Aboud S, Giovannucci EL, Mugusi FM and Fawzi WW. Vitamin D and HIV progression among Tanzanian adults initiating antiretroviral therapy. PLoS One. 2012;7(6):e40036. PMCID: PMC3386915
• Rwebembera A, Sudfeld CR, Manji KP, Duggan C, Aboud S and Fawzi WW. Prevalence and Risk Factors for Vitamin D Deficiency Among Tanzanian HIV-Exposed Uninfected Infants. J Trop Pediatr. 2013 Oct;59(5):426- 9. PMCID: PMC3789521 [Available on 2014/10/1]
• Sudfeld CR, Duggan C, Histed A, Manji KP, Meydani SN, Aboud S, Wang M, Giovannucci EL and Fawzi WW. Effect of multivitamin supplementation on measles vaccine response among HIV-exposed uninfected Tanzanian infants. Clin Vaccine Immunol. 2013 Aug;20(8):1123-32. PMCID: PMC3754503 [Available on 2014/2/1]
• Sudfeld CR, Giovannucci EL, Isanaka S, Aboud S, Mugusi FM, Wang M, Chalamilla G and Fawzi WW. Vitamin D status and incidence of pulmonary tuberculosis, opportunistic infections, and wasting among HIV- infected Tanzanian adults initiating antiretroviral therapy. J Infect Dis. 2013 Feb 1;207(3):378-85. PMCID: PMC3537448 [Available on 2014/2/1]
• Sudfeld CR, Isanaka S, Aboud S, Mugusi FM, Wang M, Chalamilla GE and Fawzi WW. Association of serum albumin concentration with mortality, morbidity, CD4 T-cell reconstitution among tanzanians initiating antiretroviral therapy. J Infect Dis. 2013 May 1;207(9):1370-8. PMCID: PMC3610420 [Available on 2014/5/1]
• Sudfeld CR, Isanaka S, Mugusi FM, Aboud S, Wang M, Chalamilla GE, Giovannucci EL and Fawzi WW. Weight change at 1 mo of antiretroviral therapy and its association with subsequent mortality, morbidity, and CD4 T cell reconstitution in a Tanzanian HIV-infected adult cohort. Am J Clin Nutr. 2013 Jun;97(6):1278-87. PMCID: PMC3652924 [Available on 2014/6/1]
• Sudfeld CR, Mugusi FM and Fawzi WW. Reply to Seraphin. J Infect Dis. 2013 May 15;207(10):1623-4. PMCID: PMC3627199 [Available on 2014/5/15]
• Fataki MR, Kisenge RR, Sudfeld CR, Aboud S, Okuma J, Mehta S, Spiegelman D and Fawzi WW. Effect of Zinc Supplementation on Duration of Hospitalization in Tanzanian Children Presenting with Acute Pneumonia. J Trop Pediatr. 2013 Nov 5. [Epub ahead of print] (PMC Journal – in Process)

Brian Joseph Sharkey (2008-2013)
Current Position: Associate Director, Global Biometric Sciences, Bristol-Myers Squibb, Princeton, NJ

Publications while in training include:

• Sharkey B, Lok J, Hughes MD. Estimation of the Cumulative Incidence Function Under Multiple Censoring Mechanisms. Biometrics. Submitted.

Ravi Goyal (2008-2012)
Current Position: Statistician, Mathematica Policy Research

Publications while in training include:

• Goyal R, Wang R, DeGruttola V. Editorial commentary: network epidemic models: assumptions and interpretations. Clin Infect Dis. 2012 Jul; 55(2):276-8. PMCID:PMC3403840
• Wang R, Goyal R, Lei Q, Essex M, De Gruttola V. Sample size considerations in the design of cluster randomized trials. Submitted.

Alisa Stephens Shields (2007-2012)
Current Position: Assistant Professor, Biostatistics Unit, University of Pennsylvania

Publications while in training include:

• Phillips KA, Ribi K, Sun Z, Stephens A, Thompson A, Harvey V, Thurlimann B, Cardoso F, Pagani O, Coates AS, Goldhirsch A, Price KN, Gelber RD and Bernhard J. Cognitive function in postmenopausal women receiving adjuvant letrozole or tamoxifen for breast cancer in the BIG 1-98 randomized trial. Breast. 2010 Oct;19(5):388-95. PMCID: PMC2921449
• Martin CR, Dasilva DA, Cluette-Brown JE, Dimonda C, Hamill A, Bhutta AQ, Coronel E, Wilschanski M, Stephens AJ, Driscoll DF, Bistrian BR, Ware JH, Zaman MM and Freedman SD. Decreased postnatal docosahexaenoic and arachidonic acid blood levels in premature infants are associated with neonatal morbidities. J Pediatr. 2011 Nov;159(5):743-9 e1-2. PMCID: PMC3701520
• Stephens AJ, Tchetgen Tchetgen EJ and De Gruttola V. Augmented generalized estimating equations for improving efficiency and validity of estimation in cluster randomized trials by leveraging cluster-level and individual-level covariates. Stat Med. 2012 May 10;31(10):915-30. PMCID: PMC3495191
• Stephens AJ, Tchetgen Tchetgen EJ and De Gruttola V. Flexible Covariate-adjusted exact tests of randomized treatment effects with application to a trial of HIV education. The Annals of Applied Statistics. Submitted.

Miles Ott (2008-2009)
Current Position: Assistant Professor, Smith College, Statistical and Data Sciences Program, Northhampton, MA

Publications while in training include:

• Ott M, Shaw S, Danilla R, Lynfield R. Lessons Learned from the 1918-1919 Influenza Pandemic in Minneapolis and St. Paul, Minnesota. Public Health Reports. 2007, 122: 803-809 PMCID:PMC1997248 Ott MQ, Tanser F, Lurie M, Barnighausen T, Newell M. Age-gaps in sexual partnerships in rural KwaZulu- Natal: seeing beyond sugar daddies. AIDS. 2011, 25(6):861-863 PMCID: PMC3117250
• Ott MQ, Corliss H, Wypij D, Rosario M, Austin SB. Stability and Change in Self-Reported Sexual Orientation Identity in Young People: Application of Mobility Metrics. Archives of Sexual Behavior. 2011: 1-14 . PMCID:PMC3081371
• Ott MQ, Wypij D, Corliss H, Rosario M, Reisner S, Gordon A, Austin SB. Repeated changes in reported sexual orientation identity linked to substance use behaviors in youth. Journal of Adolescent Health. 2013, 52(4): 465- 472. PMCID: PMC3608814

Jessica Minnier (2007-2012)
Current Position: Assistant Professor, Oregon Health & Science University, Portland, OR

Publications while in training include:

• McDaniel S, Minnier J, Betensky RA, Mohapatra G, Shen Y, Gusella JF, Louis DN and Cai T. Assessing Population Level Genetic Instability via Moving Average. Stat Biosci. 2010 Dec;2(2):120-36. PMCID: PMC3409593
• Minnier J, Tian L and Cai T. A Perturbation Method for Inference on Regularized Regression Estimates. J Am Stat Assoc. 2011 Jan 1;106(496):1371-82. PMCID: PMC3404855
• Minnier J, Liu J and Cai T. Risk Classification with an Adaptive Naive Bayes Kernel Machine Model. Am J Epidemiol. [Meeting Abstract]. 2011 Jun;173:S16-S. [Abstract]
• Perlis RH, Iosifescu DV, Castro VM, Murphy SN, Gainer VS, Minnier J, Cai T, Goryachev S, Zeng Q, Gallagher PJ, Fava M, Weilburg JB, Churchill SE, Kohane IS and Smoller JW. Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model. Psychol Med. 2012 Jan;42(1):41-50. PMCID: PMC3837420
• Minnier J, Yuan, M, Liu JS, Cai T. Risk Classification with an Adaptive Naive Bayes Kernel Machine Model. (submitted) (An earlier version won an ENAR Distinguished Student Paper Award and a David P. Byar Young Investigator Travel Award for JSM.)

Lauren Hund (2007-2012)
Current Position: Statistician, Sandia National Laboratories

Publications while in training include:

• Tanser F, Barnighausen T, Hund L, Garnett GP, McGrath N and Newell ML. Effect of concurrent sexual partnerships on rate of new HIV infections in a high-prevalence, rural South African population: a cohort study. Lancet. 2011 Jul 16;378(9787):247-55. PMCID: PMC3141142
• Hund Land Pagano M. Estimating HIV prevalence from surveys with low individual consent rates: annealing individual and pooled samples. Emerg Themes Epidemiol. 2013;10(1):2. PMCID: PMC3649931
• Hedt-Gauthier BL, Mitsunaga T, Hund L, Olives C and Pagano M. The effect of clustering on lot quality assurance sampling: a probabilistic model to calculate sample sizes for quality assessments. Emerg Themes Epidemiol. 2013 Oct 26;10(1):11. [Epub ahead of print] PMCID:PMC3819670
• Hund L, Northrop-Clewes CA, Nazario R, Suleymanova D, Mirzoyan L, Irisova M, Pagano M, Valadez JJ. A novel approach to evaluating the iron and folate status of women of reproductive age in Uzbekistan after 3 years of flour fortification with micronutrients. PLoS One. 2013 Nov 19;8(11):e79726. doi: 10.1371/journal.pone.0079726. PMCID:PMC3833927

Brian Claggett (2007-2012)
Current Position: Assistant Professor of Medicine, Harvard Medical School / Brigham and Women’s Hospital

Publications while in training include:

• Claggett B, Lagakos SW and Wang R. Augmented cross-sectional studies with abbreviated follow-up for estimating HIV incidence. Biometrics. 2012 Mar;68(1):62-74. PMCID: PMC3182305
• Claggett Band Wei LJ. Analytical issues regarding rosiglitazone meta-analysis. Arch Intern Med. [Letter]. 2011 Jan 24;171(2):179-80; author reply 80.
• Turcotte JF, Wong K, Mah SJ, Dieleman LA, Kao D, Kroeker K, Claggett B, Saltzman JR, Wine E, Fedorak RN and Liu JJ. Increased epithelial gaps in the small intestine are predictive of hospitalization and surgery in patients with inflammatory bowel disease. Clin Transl Gastroenterol. 2012;3:e19. PMCID: PMC3412678
• Cheng S, Gupta DK, Claggett B, Sharrett AR, Shah AM, Skali H, Takeuchi M, Ni H and Solomon SD. Differential influence of distinct components of increased blood pressure on cardiovascular outcomes: from the atherosclerosis risk in communities study. Hypertension. 2013 Sep;62(3):492-8. PMCID:PMC3828292
• Claggett B, Wei LJ and Pfeffer MA. Moving beyond our comfort zone. Eur Heart J. [Comment]. 2013 Mar;34(12):869-71.
• Kong J, Spaeth R, Cook A, Kirsch I, Claggett B, Vangel M, Gollub RL, Smoller JW and Kaptchuk TJ. Are all placebo effects equal? Placebo pills, sham acupuncture, cue conditioning and their association. PLoS One. 2013;8(7):e67485. PMCID: PMC3729687
• Roca GQ, Redline S, Punjabi N, Claggett B, Ballantyne CM, Solomon SD, Shah AM. Sleep Apnea Is Associated with Subclinical Myocardial Injury in the Community. The ARIC-SHHS Study. Am J Respir Crit Care Med. 2013 Dec 15;188(12):1460-5. doi: 10.1164/rccm.201309-1572OC. (Pub Med Journal – In Process)
• Santos AB, Kraigher-Krainer E, Bello N, Claggett B, Zile MR, Pieske B, Voors AA, McMurray JJ, Packer M, Bransford T, Lefkowitz M, Shah AM and Solomon SD. Left ventricular dyssynchrony in patients with heart failure and preserved ejection fraction. Eur Heart J. 2013 Oct 27. [Epub ahead of print] (Pub Med Journal – In Process)
• Zhao L, Tian L, Cai T, Claggett Band Wei LJ. Effectively Selecting a Target Population for a Future Comparative Study. J Am Stat Assoc. 2013 Jan 1;108(502):527-39. PMCID: PMC3775385 [Available on 2014/1/1]
• Wei ES, Claggett B, Greenberg P, Wei LJ. An effective way to quantify the safety profile of a drug or device when background toxicity rates are low”. Update Magazine. (not peer reviewed)

Wei (Julia) Wu (2007-2013)
Current Position: Research Associate, Department of Epidemiology, Harvard T.H. Chan School of Public Health

Publications while in training include:

• McCutchan JA, Wu JW, Robertson K, Koletar SL, Ellis RJ, Cohn S, Taylor M, Woods S, Heaton R, Currier J and Williams PL. HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS. 2007 May 31;21(9):1109-17.
• Robertson KR, Smurzynski M, Parsons TD, Wu K, Bosch RJ, Wu J, McArthur JC, Collier AC, Evans SR and Ellis RJ. The prevalence and incidence of neurocognitive impairment in the HAART era. AIDS. 2007 Sep 12;21(14):1915-21.
• Chow D, Chen H, Glesby MJ, Busti A, Souza S, Andersen J, Kohrs S, Wu Jand Koletar SL. Short-term ezetimibe is well tolerated and effective in combination with statin therapy to treat elevated LDL cholesterol in HIV-infected patients. AIDS. 2009 Oct 23;23(16):2133-41. PMCID: PMC2782438
• Fife KH, Wu JW, Squires KE, Watts DH, Andersen JW and Brown DR. Prevalence and persistence of cervical human papillomavirus infection in HIV-positive women initiating highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):274-82. PMCID: PMC2742168
  Williams P, Wu J, Cohn S, Koletar S, McCutchan J, Murphy R and Currier J. Improvement in lipid profiles over 6 years of follow-up in adults with AIDS and immune reconstitution. HIV Med. 2009 May;10(5):290-301. PMCID: PMC2778216
• Wu JW*, Xing H* (co-first authors), Liao L, Tchetgen E, Lockman S, Wang Z, Su B, De Gruttola V, Lipsitch M, Ruan Y, Cui WG, Seage GR△, Shao YM△ (co-senior authors). Elevated Risk of Mortality Associated with Emergence of Drug-resistance Mutations among HIV Patients on First-line HAART at Two Sentinel Sites in China. Manuscript Submitted.
• Wu JW, Lockman S, Xing H, De Gruttola V, Liao L, Tchetgen E, Wang Z, Su B, Ruan Y, Cui WG, Lipsitch M, Shao YM1, Seage GR1 (co-senior authors). Evolution of HIV-1 Drug-Resistance Mutations and Viral Loads among HIV Patients in China on Failing First-line HAART. Manuscript in preparation.
• Wu JW, Seage GR, Lockman S, De Gruttola V, Tchetgen E, Shao YM, Lipsitch M. Modeling the Impact of Delayed Regimen Switching on the Heterosexual Transmission of HIV Drug-Resistance Strains in Two Central Provinces in China. Manuscript in preparation.

Leigh Elizabeth Ogburn (2006-2011)
Current Position: Assistant Professor, Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health

Publications while in training include:

• Heiman GA, Ogburn E, Gorroochurn P, Keyes KM, Hasin D. Evidence for a two-stage model of dependence using the NESARC and its implications for genetic association studies. Drug Alcohol Depend. 2008 Jan 1;92(1- 3):258-66. PMCID: PMC2266584
• Blanco C, Ogburn E, Pérez de Los Cobos J, Lujan J, Nunes EV, Grant B, Liu SM, Hasin DS.DSM-IV criteria- based clinical subtypes of cannabis use disorders: results from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). Drug Alcohol Depend. 2008 Jul 1;96(1-2):136-44. PMCID:PMC3850288
• Ogburn ELand VanderWeele TJ. Analytic results on the bias due to nondifferential misclassification of a binary mediator. Am J Epidemiol. 2012 Sep 15;176(6):555-61. PMCID: PMC3530348
• Ogburn ELand VanderWeele TJ. On the nondifferential misclassification of a binary confounder. Epidemiology. 2012 May;23(3):433-9. PMCID: PMC3365922
• VanderWeele TJ, Valeri L and Ogburn EL. The role of measurement error and misclassification in mediation analysis: mediation and measurement error. Epidemiology. 2012 Jul;23(4):561-4. PMCID: PMC3367328
• Cacioppo JT, Cacioppo S, Gonzaga GC, Ogburn ELand VanderWeele TJ. Marital satisfaction and break-ups differ across on-line and off-line meeting venues. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10135-40. PMCID: PMC3690854
• Ogburn EL, VanderWeeleTJ . Bias Attenuation Results for Nondifferentially Mismeasured Ordinal and Coarsened Confounders. Biometrika. 2013;100(1):241-248. PMCID: PMC3761876
• Ogburn EL(In Press). Discussion of “Mediation analysis without sequential ignorability: Using baseline covariates interacted with random assignment as instrumental variables” by Dylan Small. Journal of Statistical Research.
• Ogburn EL, VanderWeele TJ. Causal Diagrams for Interference and Contagion. Statistical Science, under review.
• Ogburn EL, Rotnitzky A, Robins JM. Doubly Robust Estimation of the Local Average Treatment Effect Curve. Journal of the Royal Statistical Society, Series B, under revision.
• Ogburn EL, Richardson TJ, Robins JM.Variation independent reparameterization of models for the multiplicative local average treatment effect and the relative risk curves. In preparation for Journal of the American Statistical Association:Theory and Methods.
• Ogburn EL, Christakis NA, VanderWeele TJ. Identification of Contagion and Infectiousness in Social Networks. Inpreparation for Journal of the American Statistical Association: Applications and Case Studies.
• Cacioppo JT, Cacioppo S, Gonzaga G, Ogburn EL, VanderWeele TJ. Marriage and Divorce in America: Does Meeting Online (and How you Meet Online) Predict Outcomes? In preparation for Science.

Mariel Finucane (2006-2011)
Current Position: Associate Director of Data Science and Statistics, Mathematica Policy Research

Publications while in training include:

• Kieffer TL, Finucane MM, Nettles RE, Quinn TC, Broman KW, Ray SC, Persaud D and Siliciano RF. Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads. J Infect Dis. 2004 Apr 15;189(8):1452-65.
• Finucane MM, Samet JH and Horton NJ. Translational methods in biostatistics: linear mixed effect regression models of alcohol consumption and HIV disease progression over time. Epidemiol Perspect Innov. 2007;4:8. PMCID: PMC2147003
• Novitsky V, Woldegabriel E, Kebaabetswe L, Rossenkhan R, Mlotshwa B, Bonney C, Finucane M, Musonda R, Moyo S, Wester C, van Widenfelt E, Makhema J, Lagakos S and Essex M. Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection. J Acquir Immune Defic Syndr. 2009 Jan 1;50(1):65-76. PMCID: PMC2701379
• Finucane MMand Finucane TE. Discontinuing donepezil or starting memantine for Alzheimer’s disease. N Engl J Med. 2012 Jun 7;366(23):2227-8; author reply 8. [Comment
• Stevens GA, Finucane MM, Paciorek CJ, Flaxman SR, White RA, Donner AJ and Ezzati M. Trends in mild, moderate, and severe stunting and underweight, and progress towards MDG 1 in 141 developing countries: a systematic analysis of population representative data. Lancet. 2012 Sep 1;380(9844):824-34. PMCID: PMC3443900
• Stevens GA, Singh GM, Lu Y, Danaei G, Lin JK, Finucane MM, Bahalim AN, McIntire RK, Gutierrez HR, Cowan M, Paciorek CJ, Farzadfar F, Riley L and Ezzati M. National, regional, and global trends in adult overweight and obesity prevalences. Popul Health Metr. 2012;10(1):22. PMCID: PMC3543235
• Ladau J, Sharpton TJ, Finucane MM, Jospin G, Kembel SW, O’Dwyer J, Koeppel AF, Green JL and Pollard KS. Global marine bacterial diversity peaks at high latitudes in winter. ISME J. 2013 Sep;7(9):1669-77. PMCID: PMC3749493
• Finucane MM,Rowley CF, Paciorek CJ, Essex M, Pagano M (2014) Estimating the prevalence of transmitted HIV drug resistance using pooled samples. Stat Methods Med Res. Accepted for publication

Jeffrey Anderson (2006-2012)
Current Position: Research Investigator, HealthPartners Institute

Publications while in training include:

• Anderson J, Levin M, Williams P, Seage G. Incidence and predictors of herpes zoster in pediatric HIV in the HAART era. Poster abstract presented at the 13th Conference on Retroviruses and Opportunistic Infections, February 2006, Denver, CO.
• Evans SR, Wang R, Yeh T-M, Anderson J, Haija R, McBratney-Owen PM, Peeples L, Sinha S, Xanthakis V, Rajicic N and Zhang J. Evaluation of Distance Learning in an “Introduction to Biostatistics” Class: A Case Study. Statistics Education Research Journal. 2007 Nov;6(2):59-77.
  Levin MJ, Anderson JP, Seage GR, 3rd and Williams PL. Short-term and long-term effects of highly active antiretroviral therapy on the incidence of herpes zoster in HIV-infected children. J Acquir Immune Defic Syndr. 2009 Feb 1;50(2):182-91. PMCID: PMC2748317
• Anderson JP, Tchetgen Tchetgen EJ, Seage GR, Lo Re V, Tate JP, Lim JK et al. A marginal structural model analysis of combination antiretroviral therapy and hepatic decompensation in HIV and HCV coinfected veterans. Oral abstract presented at the 16th International Workshop on HIV Observational Databases, March 2012, Athens, Greece.
• Anderson JP, Tchetgen EJ, Lo Re V 3rd, Tate JP, Williams PL, Seage GR 3rd, Horsburgh CR, Lim JK, Goetz MB, Rimland D, Rodriguez-Barradas MC, Butt AA, Klein MB, Justice AC. Antiretroviral Therapy Reduces the Rate of Hepatic Decompensation among HIV- and Hepatitis C Virus-Coinfected Veterans. Clin Infect Dis. 2013 Dec 20. [Epub ahead of print]. (PMC Journal – In process)
• Anderson JP, Horsburgh CR, Williams PL, Tchetgen Tchetgen EJ, Nunes D, Cotton DC et al. Immunologic and virologic predictors of liver disease progression in HIV and hepatitis C virus coinfected injecting drug users. [To be resubmitted]
• Schieffelin JS, Williams PL, Djokic D, Anderson JP, Nachman S, Oleske J, Seage GR, Van Dyke R. CNS vasculitis in HIV infected children followed in the PACTG 219/219C study. [Under Review]
• Anderson JP, Seage GR, Tchetgen Tchetgen EJ, Lo Re V, Tate JP, Williams PL et al. Interferon-based therapy and hepatic decompensation in HIV and HCV coinfected veterans. [To be submitted]

Rui Wang (2005-2008)
Current Position: Associate Professor of Population Medicine, Harvard Medical School

Publications while in training include:

• Jacobson J, Lederman M, Spritzler J, Valdez H, Tebas P, Skowron G, Wang R, Jackson JB, Fox L,and Gilbert M, for the ACTG 5041 Team. Granulocyte-Macrophage Colony-Stimulating Factor induces modest increases in plasma HIV RNA and CD4 lymphocyte counts in patients with uncontrolled HIV infection. The Journal of Infectious Diseases 2003; 188:1804-1814.
• Malhotra U, Bosch RJ, Chan E, Wang R, Fischl MA, Collier AC, and McElrath JM. Association of T cell proliferative responses and phenotype with virus control in chronic progressive HIV-1 disease. The Journal of Infectious Disease 2004; 189:515-519.
• Malhotra U, Bosch RJ, Wang R, Collier A, McElrath MJ. Effect of adjunct Hydroxyurea on helper T cell immunity in HIV-1-Infected patients with virologic suppression. AIDS Research and Human Retroviruses 2004; 20: 807-12.
• Benson CA, Vaida F, Havlir DV, Downey GF, Lederman MM, Gulick RM, Glesby MJ, Wantman M, Bixby CJ, Rinehart AR, Snyder S, Wang R, Patel S and Mellors JW. A randomized trial of treatment interruption before optimized antiretroviral therapy for persons with drug-resistant HIV: 48-Week virologic results of ACTG A5086. Journal of Infectious Diseases. 2006 Nov;194(9):1309-18.
• Bosch RJ, Wang R, Vaida F, Lederman MM and Albrecht MA. Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2006 Dec;43(4):433-5.
• Jacobson JM, Bucy RP, Spritzler J, Saag MS, Eron JJ, Coombs RW, Wang R, Fox L, Johnson VA, Cu-Uvin S, Cohn SE, Mildvan D, O’Neill D, Janik J, Purdue L, O’Connor DK, Di Vita C and Frank I. Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP 1452, promotes host control of HIV replication: The results of AIDS Clinical Trials Group 5068. Journal of Infectious Diseases. 2006 Sep;194(5):623-32.
• Evans SR, Wang R, Yeh T-M, Anderson J, Haija R, McBratney-Owen PM, Peeples L, Sinha S, Xanthakis V, Rajicic N and Zhang J. Evaluation of Distance Learning in an “Introduction to Biostatistics” Class: A Case Study. Statistics Education Research Journal. 2007 Nov;6(2):59-77.
• Wang R, Lagakos SW, Ware JH, Hunter DJ and Drazen JM. Statistics in medicine–reporting of subgroup analyses in clinical trials. N Engl J Med. 2007 Nov 22;357(21):2189-94.
• Novitsky V, Wang R, Kebaabetswe L, Greenwald J, Rossenkhan R, Moyo S, Musonda R, Woldegabriel E, Lagakos S and Essex M. Better control of early viral replication is associated with slower rate of elicited antiviral antibodies in the detuned enzyme immunoassay during primary HIV-1C infection. J Acquir Immune Defic Syndr. 2009 Oct 1;52(2):265-72. PMCID: PMC2815186
• Novitsky V, Wang R, Margolin L, Baca J, Kebaabetswe L, Rossenkhan R, Bonney C, Herzig M, Nkwe D, Moyo S, Musonda R, Woldegabriel E, van Widenfelt E, Makhema J, Lagakos S and Essex M. Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection. PLoS One. 2009;4(11):e7727. PMCID: PMC2768328
• Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH and Shivdasani RA. Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer. 2009 Aug 4;101(3):465-72. PMCID: PMC2720232
• Wang R and Lagakos SW. On the use of adjusted cross-sectional estimators of HIV incidence. J Acquir Immune Defic Syndr. 2009 Dec;52(5):538-47. PMCID: PMC3682673
• Wang R and Lagakos SW. Inference after variable selection using restricted permutation methods. Can J Stat. 2009 Dec 1;37(4):625-44. PMCID: PMC2848082
• Finkelstein DM, Wang R, Ficociello LH and Schoenfeld DA. A score test for association of a longitudinal marker and an event with missing data. Biometrics. 2010 Sep;66(3):726-32. PMCID: PMC2952639
• Novitsky V, Wang R, Bussmann H, Lockman S, Baum M, Shapiro R, Thior I, Wester C, Wester CW, Ogwu A, Asmelash A, Musonda R, Campa A, Moyo S, van Widenfelt E, Mine M, Moffat C, Mmalane M, Makhema J, Marlink R, Gilbert P, Seage GR, 3rd, DeGruttola V and Essex M. HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the “test-and-treat” approach to reduce HIV transmission. PLoS One. 2010;5(4):e10148. PMCID: PMC2853582
• Novitsky V, Wang R, Lagakos S and Essex M. HIV-1 Subtype C Phylodynamics in the Global Epidemic. Viruses. 2010 Jan;2(1):33-54. PMCID: PMC3185553
• Novitsky V, Wang R, Margolin L, Baca J, Moyo S, Musonda R and Essex M. Dynamics and timing of in vivo mutations at Gag residue 242 during primary HIV-1 subtype C infection. Virology. 2010 Jul 20;403(1):37-46. PMCID: PMC2884147
• Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J and Haber DA. A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 2010 Mar 15;70(6):2158-64. PMCID: PMC2881662
• Wang Rand Lagakos SW. Augmented cross-sectional prevalence testing for estimating HIV incidence. Biometrics. 2010 Sep;66(3):864-74. PMCID: PMC2889247
• Wang R, Lagakos SW and Gray RJ. Testing and interval estimation for two-sample survival comparisons with small sample sizes and unequal censoring. Biostatistics. 2010 Oct;11(4):676-92. PMCID: PMC2950789
• Abi-Raad R, Boutrus R, Wang R, Niemierko A, Macdonald S, Smith B and Taghian AG. Patterns and risk factors of locoregional recurrence in T1-T2 node negative breast cancer patients treated with mastectomy: implications for postmastectomy radiotherapy. Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):e151-7. PMCID: PMC3722592
• Haun JB, Castro CM, Wang R, Peterson VM, Marinelli BS, Lee H and Weissleder R. Micro-NMR for rapid molecular analysis of human tumor samples. Sci Transl Med. 2011 Feb 23;3(71):71ra16. PMCID: PMC3086073
• Novitsky V, Ndung’u T, Wang R, Bussmann H, Chonco F, Makhema J, De Gruttola V, Walker BD and Essex M. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS. 2011 Jul 31;25(12):1515-22. PMCID: PMC3544358
• Novitsky V, Wang R, Baca J, Margolin L, McLane MF, Moyo S, van Widenfelt E, Makhema J and Essex M. Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection. Virology. 2011 Dec 20;421(2):119-28. PMCID: PMC3210886
• Novitsky V, Wang R, Margolin L, Baca J, Rossenkhan R, Moyo S, van Widenfelt E and Essex M. Transmission of single and multiple viral variants in primary HIV-1 subtype C infection. PLoS One. 2011;6(2):e16714. PMCID: PMC3048432
• Claggett B, Lagakos SW and Wang R. Augmented cross-sectional studies with abbreviated follow-up for estimating HIV incidence. Biometrics. 2012 Mar;68(1):62-74. PMCID: PMC3182305
• Goyal R, Wang Rand DeGruttola V. Editorial commentary: network epidemic models: assumptions and interpretations. Clin Infect Dis. 2012 Jul;55(2):276-8. PMCID: PMC3403840
• HIV Modelling Consortium Treatment as Prevention Editorial Writing Group:, Bärnighausen T, Becker S, Bendavid E, Bershteyn A, Blandford J, Boily MC, Burns D, Cambiano V, Cohen MS, Delva W, Dye C, Eaton JW, Egger M, Fraser C, Galai N, Garnett G, Ghys PD, Hallett TB, Heaton L, Holmes CB, Hontelez J, Jewell B, Keiser O, Klein D, Lima V, Long E, Lyerla R, Marais C, Meng F, Meyer-Rath G, Miller WC, Muraguri N, Nichols BE, Nigmatulina KR, Padian N, Phillips A, Pretorius C, Rousseau C, Salomon J, Sangrujee N, Serwadda D, Tanser F, Vesga JF, Vickerman P, Walker D, Wang R, Welte A, White RG, Williams B, Wilson DP, Wilson D and Zaba B. HIV treatment as prevention: models, data, and questions–towards evidence-based decision- making. PLoS Med. 2012;9(7):e1001259. PMCID: PMC3393655
• Wang R, Bosch RJ, Benson CA and Lederman MM. Drug-resistant virus has reduced ability to induce immune activation. J Acquir Immune Defic Syndr. 2012 Dec 1;61(4):e60-3. PMCID: PMC3499025 [Available on 2013/12/1]
• Billings ME, Rosen CL, Wang R, Auckley D, Benca R, Foldvary-Schaefer N, Iber C, Zee P, Redline S and Kapur VK. Is the relationship between race and continuous positive airway pressure adherence mediated by sleep duration? Sleep. 2013 Feb;36(2):221-7. PMCID: PMC3543052
• Novitsky V, Wang R, Rossenkhan R, Moyo S and Essex M. Intra-host evolutionary rates in HIV-1C env and gag during primary infection. Infect Genet Evol. 2013 Oct;19:361-8. PMCID: PMC3759599 [Available on 2014/10/1]
• Wang Rand Ware JH. Detecting moderator effects using subgroup analyses. Prev Sci. 2013 Apr;14(2):111- 20. PMCID: PMC3193873 [Available on 2014/4/1]
• Wang R, Weng J, Moyo S, Pain D, Barr CD, Maruapula D, Mongwato D, Makhema J, Novitsky V and Essex M. Short communication: effect of short-course antenatal zidovudine and single-dose nevirapine on the BED capture enzyme immunoassay levels in HIV type 1 subtype C infection. AIDS Res Hum Retroviruses. 2013 Jun;29(6):901-6. PMCID: PMC3653368 [Available on 2014/6/1]
• Moyo S, Lecuyer T, Wang R, Gaseitsiwe S, Weng J, Musonda R, Bussmann H, Mine M, Engelbrecht S, Makhema J, Marlink RG, Baum MK, Novitsky V, Essex M. Evaluation of the False Recent Classification Rates of Multi-Assay Algorithms in Estimating HIV-1 Subtype C Incidence. AIDS Res Hum Retroviruses. 2013 Sep 6. [Epub ahead of print] (Pub Med Journal – In Process)
• Novitsky V, Bussmann H, Logan A, Moyo S, van Widenfelt E, Okui L, Mmalane M, Baca J, Buck L, Phillips E, Tim D, McLane MF, Lei Q, Wang R, Makhema J, Lockman S, De Gruttola V, Essex M. Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana. PLoS One, 2013; 8(12): e80589. PMCID: PMC3859477
• Weinstock T, Rosen CL, Marcus CL, Garetz S, Mitchell RB, Amin R, Paruthi S, Katz E, Arens R, Weng J, Ross K, Chervin RD, Ellenberg S, Wang R, Redline S. Predictors of obstructive sleep apnea severity in adenotonsillectomy candidates. Sleep, 2014; accepted for publication.
• Carnegie NB, Wang R, Novitsky V, De Gruttola V. Linkage of viral sequences among HIV-infected village residents in Botswana: estimation of linkage rates in the presence of missing data. PLOS Computational Biology, 2014; accepted for publication.
• Gleason K, Shin D, Rueschman M, Weinstock T, Wang R, Ware JH, Mittleman MA, Redline S. Recruitment Yields in a Randomized Controlled Study of Cardiovascular Disease Reduction in Sleep Apnea: Impact of Mode and Source of Recruitment. Submitted.
• Wang R, Goyal R, Lei Q, Essex M, De Gruttola V. Sample size considerations in the design of cluster randomized trials. Submitted.

Shannon Stock (2005-2011)
Current Position: Assistant Professor, Department of Mathematics and Computer Science, College of the Holy Cross

Publications while in training include:

• Shipton LK, Wester CW, Stock S, Ndwapi N, Gaolathe T, Thior I, Avalos A, Moffat HJ, Mboya JJ, Widenfelt E, Essex M, Hughes MD and Shapiro RL. Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana. Int J Tuberc Lung Dis. 2009 Mar;13(3):360-6. PMCID: PMC2696339
• Etcoff NL, Stock S, Haley LE, Vickery SA and House DM. Cosmetics as a feature of the extended human phenotype: modulation of the perception of biologically important facial signals. PLoS One. 2011;6(10):e25656. PMCID: PMC3185017
• Hammond SP, Gagne LS, Stock SR, Marty FM, Gelman RS, Marasco WA, Poritz MA and Baden LR. Respiratory virus detection in immunocompromised patients with FilmArray respiratory panel compared to conventional methods. J Clin Microbiol. 2012 Oct;50(10):3216-21. PMCID: PMC3457462
• Stock Sand DeGruttola V. Recursive partitioning for monotone missing at random longitudinal markers. Stat Med. 2013 Mar 15;32(6):978-94. PMCID: PMC3754451 [Available on 2014/3/15]
• Pena-Cruz V, Etemad B, Chatziandreou N, Nyein PH, Stock S, Reynolds SJ, Laeyendecker O, Gray RH, Serwadda D, Lee SJ, Quinn TC, Sagar M. HIV-1 envelope replication and alpha4beta7 utilization among newly infected subjects and their corresponding heterosexual partners. Retrovirology. 2013 Dec 26;10(1):162. [Epub ahead of print] (PMC Journal – In Process)

Maile Ray (2005-2012)
Current Position: Scientist/Postdoctoral Fellow, Mt. Sinai School of Medicine, Division of General Internal Medicine, New York, NY

Publications while in training include:

• HIV-CAUSAL Collaboration, Ray M, Logan R, Sterne JA, Hernandez-Diaz S, Robins JM, Sabin C, Bansi L, van Sighem A, de Wolf F, Costagliola D, Lanoy E, Bucher HC, von Wyl V, Esteve A, Casbona J, del Amo J, Moreno S, Justice A, Goulet J, Lodi S, Phillips A, Seng R, Meyer L, Perez-Hoyos S, Garcia de Olalla P and Hernan MA. The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals. AIDS. 2010 Jan 2;24(1):123-37. PMCID: PMC2920287
• Ray M, Wisnivesky JP, Sofianou A, Martynenko M, Wolf MS, Leventhal H and Federman AD. COPD Beliefs In Older Adults And Their Associations With Health Literacy. American Thoracic Society 2013 International Conference. 2013 May 17-22:A5511. [Abstract]

Casey Olives (2005-2010)
Current Position: Head of Data Science, Convoy Inc, Seattle, WA

Publications while in training include:

• Hedt BL, Olives C, Pagano M, and Valadez JJ. Large Country- Lot Quality Assurance Sampling: A New Method for Rapid Monitoring and Evaluation of Health, Nutrition and Population Programs at Sub-National Level (A Protocol). HNP Discussion Paper Series, 2008.
• Olives C, Pagano M, Deitchler M, Hedt BL, Egge K and Valadez JJ. Cluster designs to assess the prevalence of acute malnutrition by lot quality assurance sampling: a validation study by computer simulation. J R Stat Soc Ser A Stat Soc. 2009 Apr;172(2):495-510. PMCID: PMC2784900
• Olives C and Pagano M. Bayes-LQAS: classifying the prevalence of global acute malnutrition. Emerg Themes Epidemiol. 2010;7(1):3. PMCID: PMC2903572
• Olives C, Valadez JJ, Brooker SJ and Pagano M. Multiple category-lot quality assurance sampling: a new classification system with application to schistosomiasis control. PLoS Negl Trop Dis. 2012;6(9):e1806. PMCID: PMC3435238
• Hedt-Gauthier BL, Mitsunaga T, Hund L, Olives C and Pagano M. The effect of clustering on lot quality assurance sampling: a probabilistic model to calculate sample sizes for quality assessments. Emerg Themes Epidemiol. 2013 Oct 26;10(1):11. PMCID:PMC3819670
• Olives C, Myerson R, Mokdad AH, Murray CJ and Lim SS. Prevalence, awareness, treatment, and control of hypertension in United States counties, 2001-2009. PLoS One. 2013;8(4):e60308. PMCID: PMC3618269
• Olives C and Pagano M. Choosing a design to fit the situation: how to improve specificity and positive predictive values using Bayesian lot quality assurance sampling. Int J Epidemiol. 2013 Feb;42(1):346-55. PMCID: PMC3600627
• Smith JL, Sturrock HJ, Olives C, Solomon AW and Brooker SJ. Comparing the performance of cluster random sampling and integrated threshold mapping for targeting trachoma control, using computer simulation. PLoS Negl Trop Dis. 2013 Aug;7(8):e2389. PMCID: PMC3749968

Matthew Austin (2005-2010)
Current Position: Quantitative Researcher, AJO Partners

Publications while in training include:

• Austin, Matthew D.; Barr, Christopher D.; and DeGruttola, Victor, “Estimating HIV prevalence in the presence of spatial variation” (October 2012). COBRA Preprint Series. Working Paper 98. http://biostats.bepress.com/cobra/art98
• Austin MD and Betensky RA. Eliminating Bias Due to Censoring in Kendall’s Tau Estimators for Quasi- Independence of Truncation and Failure. Computational Statistics and Data Analysis. (accepted for publication)
• Austin MD, Simon DK, Betensky RA. Computationally simple estimation and improved efficiency for special cases of double truncation. Lifetime Data Analysis (accepted for publication).
• Austin MD, Betensky RA, Cudkowicz, ME. Methods for multiply truncated survival data: application to a study in Amyotrophic Lateral Sclerosis. In revision for Biometrics.
• Austin MD and Betensky RA. Estimating a Survival Distribution in the Presence of Dependent Left Truncation and Right Censoring. In revision for Biostatistics.

Jing (Jenny) Zhang (2004-2008)
Current Position: Director, Oncology Biostatistics at Nektar Therapeutics

Publications while in training include:

• Bernhard J, Zahrieh D, Zhang JJ, Martinelli G, Basser R, Hurny C, Forbes JF, Aebi S, Yeo W, Thurlimann B, Green MD, Colleoni M, Gelber RD, Castiglione-Gertsch M, Price KN, Goldhirsch A and Coates AS. Quality of life and quality-adjusted survival (Q-TWiST) in patients receiving dose-intensive or standard dose chemotherapy for high-risk primary breast cancer. British Journal of Cancer. 2008 Jan;98(1):25-33. PMCID: PMC2359705
• Zhang JJ and Wang M. Latent class joint model of ovarian function suppression and DFS for premenopausal breast cancer patients. Stat Med. 2010 Sep 30;29(22):2310-24. PMCID: PMC3786368
• Blumenthal GM, Cortazar P, Zhang JJ, Tang S, Sridhara R, Murgo A, Justice R and Pazdur R. FDA approval summary: sunitinib for the treatment of progressive well-differentiated locally advanced or metastatic pancreatic neuroendocrine tumors. Oncologist. 2012;17(8):1108-13. PMCID: PMC3425529
• Cruciani RA, Zhang JJ, Manola J, Cella D, Ansari B and Fisch MJ. L-carnitine supplementation for the management of fatigue in patients with cancer: an eastern cooperative oncology group phase III, randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2012 Nov 1;30(31):3864-9. PMCID: PMC3478577 [Available on 2013/11/1]
• Rothmann MD, Zhang JJ, Lu L and Fleming TR. Testing in a Prespecified Subgroup and the Intent-to-Treat Population. Drug Inf J. 2012 Mar 1;46(2):175-9. PMCID: PMC3378054
• Zhang JJ, Chen HY, He K, Tang SH, Justice R, Keegan P, Pazdur R and Sridhara R. Evaluation of Blinded Independent Central Review of Tumor Progression in Oncology Clinical Trials: A Meta-analysis. Ther Innov Regul Sci. [Review]. 2013 Mar;47(2):167-74. (FDA supported)
• Zhang JJ, Blumenthal GM, He K, Tang S, Cortazar P, Sridhara R. Overestimation of the effect size in group sequential trials. Clin Cancer Res. 2012 Sep 15;18(18):4872-6. doi: 10.1158/1078-0432.CCR-11-3118. Epub 2012 Jul 2. (FDA supported)
• Zhang JJ, Zhang L, Chen H, Murgo AJ, Dodd LE, Pazdur R and Sridhara R. Assessment of audit methodologies for bias evaluation of tumor progression in oncology clinical trials. Clin Cancer Res. 2013 May 15;19(10):2637-45. (FDA supported)
• Rothmann M, Koti K, Lee KY, Lu HL, Shen YL, Zhang JJ, Jin M and Zhou H. Evaluating and adjusting for premature censoring of progression-free survival. J Biopharm Stat. 2013;23(5):1091-105. doi: 10.1080/10543406.2013.813526.(FDA supported)
• Zhang JJ and Wang M. Alternatives to the Kaplan-Meier Estimator of Progresion-Free Survival. In preparation for journal submission.
• Rothmann M, Koti K, Lee KY, Lu HL, Shen Y, and Zhang JJ (2009). “Examining the extent and impact of missing data in oncology clinical trials.” Joint Statistical Meeting 2009 Proceedings, Biopharmaceutical Section.

Farzad Noubary (2004-2011)
Current Position: Assistant Professor, Tufts University School of Medicine, Biostatistics, Epidemiology, and Research Design (BERD) Center

Publications while in training include: 

• Fernander AF, Flisher AJ, King G, Noubary F, Lombard C, Price M and Chalton D. Gender differences in depression and smoking among youth in Cape Town, South Africa. Ethn Dis. 2006 Winter;16(1):41-50.
• King G, Guilbert P, Ward DG, Arwidson P and Noubary F. Correlates of sexual abuse and smoking among French adults. Child Abuse Negl. 2006 Jun;30(6):709-23.
• Progress Report Page 75Contact PD/PI: Pagano, Marcello
• King G, Polednak A, Fagan P, Gilreath T, Humphrey E, Fernander A, Bendel R and Noubary F. Heterogeneity in the smoking behavior of African American women. Am J Health Behav. 2006 May-Jun;30(3):237-46.
• Fay MP, Noubary F and Saul A. Robust Non-inferiority Tests for Potency of a Test Drug Against a Reference Drug: (To appear in Statistics in Biopharmaceutical Research ). Stat Biopharm Res. 2009 Aug 1;1(3):291-300. PMCID: PMC2739393
• Noubary F and Hughes MD. Assessing agreement in the timing of treatment initiation determined by repeated measurements of novel versus gold standard technologies with application to the monitoring of CD4 counts in HIV-infected patients. Stat Med. 2010 Aug 15;29(18):1932-46. PMCID: PMC2917261
• Rydzak CE, Cotich KL, Sax PE, Hsu HE, Wang B, Losina E, Freedberg KA, Weinstein MC and Goldie SJ.; CEPAC Investigators. Assessing the performance of a computer-based policy model of HIV and AIDS. PLoS One. 2010;5(9). PMCID: PMC2936574
• Walensky RP, Paltiel AD, Losina E, Morris BL, Scott CA, Rhode ER, Seage GR and Freedberg KA.; CEPAC Investigators. Test and treat DC: forecasting the impact of a comprehensive HIV strategy in Washington DC. Clin Infect Dis. 2010 Aug 15;51(4):392-400. PMCID: PMC2906630
• Ahonkhai AA, Noubary F, Munro A, Stark R, Wilke M, Freedberg KA, Wood R and Losina E.; CEPAC Investigators. Not all are lost: interrupted laboratory monitoring, early death, and loss to follow-up (LTFU) in a large South African treatment program. PLoS One. 2012;7(3):e32993. PMCID: PMC3299719
• Andrews JR, Lawn SD, Rusu C, Wood R, Noubary F, Bender MA, Horsburgh CR, Losina E, Freedberg KA and Walensky RP. The cost-effectiveness of routine tuberculosis screening with Xpert MTB/RIF prior to initiation of antiretroviral therapy: a model-based analysis. AIDS. 2012 May 15;26(8):987-95. PMCID: PMC3517815
• Andrews JR, Noubary F, Walensky RP, Cerda R, Losina E and Horsburgh CR. Risk of progression to active tuberculosis following reinfection with Mycobacterium tuberculosis. Clin Infect Dis. 2012 Mar;54(6):784-91. PMCID: PMC3284215
• Noubary F and Hughes MD. Factors affecting timing of antiretroviral treatment initiation based on monitoring CD4 counts. J Acquir Immune Defic Syndr. 2012 Nov 1;61(3):326-33. PMCID: PMC3649850
• Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, Wong VL, Pohlmann RA, Ryan US and Whitesides GM. A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med. 2012 Sep 19;4(152):152ra29. PMCID: PMC3624093
• Ramirez-Avila L, Nixon K, Noubary F, Giddy J, Losina E, Walensky RP and Bassett IV. Routine HIV testing in adolescents and young adults presenting to an outpatient clinic in Durban, South Africa. PLoS One. 2012;7(9):e45507. PMCID: PMC3447803
• Shenoy ES, Hsu H, Noubary F, Hooper DC and Walensky RP. National survey of infection preventionists: policies for discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus. Infect Control Hosp Epidemiol. 2012 Dec;33(12):1272-5. PMCID: PMC3496276 [Available on 2013/12/1]
• Hyle EP, Wood BR, Backman ES, Noubary F, Hwang J, Lu Z, Losina E, Walensky RP and Gandhi RT. High frequency of hypothalamic-pituitary-adrenal axis dysfunction after local corticosteroid injection in HIV-infected patients on protease inhibitor therapy. J Acquir Immune Defic Syndr. 2013 Aug 15;63(5):602-8. PMCID: PMC3805773 [Available on 2014/8/15]
• Pollock NR, McGray S, Colby DJ, Noubary F, Nguyen H, Nguyen TA, Khormaee S, Jain S, Hawkins K, Kumar S, Rolland JP, Beattie PD, Chau NV, Quang VM, Barfield C, Tietje K, Steele M and Weigl BH. Field Evaluation of a Prototype Paper-Based Point-of-Care Fingerstick Transaminase Test. PLoS One. 2013;8(9):e75616. PMCID: PMC3787037
• Govindasamy D, Kranzer K, van Schaik N, Noubary F, Wood R, Walensky RP, Freedberg KA, Bassett IV, Bekker LG., Linkage to HIV, TB and Non-Communicable Disease Care from a Mobile Testing Unit in Cape Town, South Africa. PLoS One. 2013 Nov 13;8(11):e80017. doi: 10.1371/journal.pone.0080017. PMCID:PMC3827432
• Ciaranello AL, Morris BL, Walensky RP, Weinstein MC, Ayaya S, Doherty K, Leroy V, Hou T, Desmonde S, Lu Z, Noubary F, Patel K, Ramirez-Avila L, Losina E, Seage Iii GR, Freedberg KA. Validation and Calibration of a Computer Simulation Model of Pediatric HIV Infection, PLoS One. 2013 Dec 13;8(12):e83389.doi:10.1371/journal.pone.0083389. PMCID:PMC3862684
• Yazdanpanah Y, Perelman J, Dilorenzo MA, Alves J, Barros H, Mateus C, Pereira J, Mansinho K, Robine M, Park JE, Ross EL, Losina E, Walensky RP, Noubary F, Freedberg KA, Paltiel AD. Routine HIV Screening in Portugal: Clinical Impact and Cost-Effectiveness. PLoS One. 2013 Dec 18;8(12):e84173. doi: 10.1371/journal.pone.0084173. PMCID:PMC3867470

Alane Izu (2004-2011)
Current Position: Biostatistician, Chris Hani Baragwanath Hospital / University of the Witwatersrand Medical School, Johannesburg

Publications while in training include: 

• Izu A, Cohen T, Mitnick C, Murray M and De Gruttola V. Bayesian methods for fitting mixture models that characterize branching tree processes: An application to development of resistant TB strains. Stat Med. 2011 Sep 30;30(22):2708-20. PMCID: PMC3219798
• Dangor Z, Izu A, Hillier K, Solomon F, Beylis N, Moore DP, Nunes MC and Madhi SA. Impact of the antiretroviral treatment program on the burden of hospitalization for culture-confirmed tuberculosis in South African children: a time-series analysis. Pediatr Infect Dis J. 2013 Sep;32(9):972-7. (not federally funded)
• Izu A, Cohen T and DeGruttola V. Bayesian estimation of mixture models with prespecified elements to compare drug resistance in treatment-naive and experienced tuberculosis cases. PLoS Comput Biol. 2013;9(3):e1002973. PMCID: PMC3605089
• Jones SA, Groome M, Koen A, Van Niekerk N, Sewraj P, Kuwanda L, Izu A, Adrian PV and Madhi SA. Immunogenicity of seven-valent pneumococcal conjugate vaccine administered at 6, 14 and 40 weeks of age in South African infants. PLoS One. 2013;8(8):e72794. PMCID: PMC3755982
• Madhi SA, Izu A, Violari A, Cotton MF, Panchia R, Dobbels E, Sewraj P, van Niekerk N, Jean-Philippe P and Adrian PV. Immunogenicity following the first and second doses of 7-valent pneumococcal conjugate vaccine in HIV-infected and -uninfected infants. Vaccine. 2013 Jan 21;31(5):777-83. PMCID: PMC3646262 [Available on 2014/1/21]

Kaveh Maghsoudi (2003-2008)
Current Position: Physician, Coastal Radiation Oncology Medical Group / Salinas Radiation Oncology Medical Center, Salinas, CA

Publications while in training include:

• Kassutto S, Maghsoudi K, Johnston MN, Robbins GK, Burgett NC, Sax PE, Cohen D, Pae E, Davis B, Zachary K, Basgoz N, D’Agata EMC, DeGruttola V, Walker BD and Rosenberg ES. Longitudinal analysis of clinical markers following antiretroviral therapy initiated during acute or early HIV type 1 infection. Clinical Infectious Diseases, 2006; 42(7): 1024-1031.
• Song JS, Maghsoudi K, Li W, Fox E, Quackenbush J and Liu XS. Microarray blob-defect removal improves array analysis. Bioinformatics, 2007; 23(8): 966-971.
• Sun JY, Xu L, Tseng H, Ciccarelli B, Fulciniti M, Hunter ZR, Maghsoudi K, Hatjiharissi E, Zhou Y, Yang G, Zhu B, Liu X, Gong P, Ioakimidis L, Sheehy P, Patterson CJ, Munshi NC, O’Connor OA and Treon SP. Histone deacetylase inhibitors demonstrate significant preclinical activity as single agents, and in combination with bortezomib in Waldenstrom’s macroglobulinemia. Clin Lymphoma Myeloma Leuk. 2011 Feb;11(1):152-6.
• Sun JY, Tseng H, Xu L, Hunter Z, Ciccarelli B, Fulciniti M, Zhu B, Maghsoudi K, Yang G, Gong P, Zhou Y, Liu X, Munshi NC, Patterson CJ and Treon SP. Vorinostat induced cellular stress disrupts the p38 mitogen activated protein kinase and extracellular signal regulated kinase pathways leading to apoptosis in Waldenstrom macroglobulinemia cells. Leuk Lymphoma. 2011 Sep;52(9):1777-86.

Bethany Hedt Gauthier (2003-2008)
Current Position: Assistant Professor of Global Health and Social Medicine, Harvard Medical School

Publications while in training include:

• Hedt BL, Wadonda-Kabondo N, Makombe S, Harries AD, Schouten EJ, Limbambala E, Hochgesang M, Aberle-Grasse J and Kamoto K. Early warning indicators for HIV drug resistance in Malawi. Antiviral Therapy, 2008; 13: 69-75.
• Makombe SD, Hochgesang M, Jahn A, Tweya H, Hedt B, Chuka S, Yu JKL, Aberle-Grasse J, Pasulani E, Bailey C, Kamoto K, Schouten EJ and Harries AD. Assessing the quality of data aggregated by antiretrovial treatment clinics in Malawi. Bulletin of the World Health Organization, 2008; 86(4): 310-314.
• Banda AC, Makombe SD, Jahn A, Tweya H, Chuka S, Yu JK, Hedt B, Weigel R, Nkhata A, Schouten EJ, Kamoto K and Harries AD. Antiretroviral therapy in the Malawi defence force: access, treatment outcomes and impact on mortality. PLoS ONE, 2008; 3(1): e1445.
• Makombe SD, Jahn A, Tweya H, Thambo L, Yu JK, Hedt B, Weigel R, Nkhata A, Schouten EJ, Kamoto K and Harries AD. A national survey of prisoners on antiretroviral therapy in Malawi: access to treatment and outcomes on therapy. World Hosp Health Serv, 2008; 44(1): 26-9.
• Hedt BL, Olives C, Pagano M, and Valadez JJ.  Large Country- Lot Quality Assurance Sampling: A New Method for Rapid Monitoring and Evaluation of Health, Nutrition and Population Programs at Sub-National Level (A Protocol).  HNP Discussion Paper Series, 2008.
• Hedt BL, Wadonda-Kabondo N, Makombe S, Harries AD, Schouten EJ, Limbambala E, Hochgesang M, Aberle-Grosse J and Kamoto K. Early warning indicators for HIV drug resistance in Malawi. Antivir Ther. 2008;13 Suppl 2:69-75. (not NIH-funded)
• Kamoto K, Aberle-Grasse J, Bello G, Bennett D, Chilima B, Harries A, Hedt B, Hosseinipour M, Limbambala E, Lowrance D, Makombe S, Matatiyo B, McNulty A, Moyo K, Schouten E, Sidibe K, Wadonda-Kabondo N, Weigel R, Yang C and (Members of the Malawi HIV Drug Resistance Task Force). Surveillance of transmitted HIV drug resistance with the World Health Organization threshold survey method in Lilongwe, Malawi. Antivir Ther. 2008;13 Suppl 2:83-7. (not NIH-funded)
• Aberle-Grasse J, Bello G, Bennett D, Chilima B, Harries A, Hedt B, Hosseinipour M, Kamoto K, Limbambala E, Lowrance D, Makombe S, Matatiyo B, McNulty A, Moyo K, Schouten E, Sidibe K, Wadonda-Kabondo N, Weigel R, Yang C.. Surveillance of transmitted HIV drug resistance with the World Health Organization threshold survey method in Lilongwe, Malawi. Antivir Ther. 2008;13 Suppl 2:83-7 (not NIH-funded)
• Makombe SD, Hochgesang M, Jahn A, Tweya H, Hedt B, Chuka S, Yu JK, Aberle-Grasse J, Pasulani O, Bailey C, Kamoto K, Schouten EJ and Harries AD. Assessing the quality of data aggregated by antiretroviral treatment clinics in Malawi. Bull World Health Organ. 2008 Apr;86(4):310-4. PMCID: PMC2647428 Makombe SD, Jahn A, Tweya H, Chuka S, Yu JK, Hedt B, Weigel R, Nkhata A, Schouten EJ, Kamoto K and Harries AD. Antiretroviral therapy in the Malawi police force: access to therapy and treatment outcomes. Malawi Med J. 2008 Mar;20(1):23-7. PMCID: PMC3345663
• Makombe SD, Jahn A, Tweya H, Thambo L, Yu JK, Hedt B, Weigel R, Nkhata A, Schouten EJ, Kamoto K and Harries AD. A national survey of prisoners on antiretroviral therapy in Malawi: access to treatment and outcomes on therapy. World Hosp Health Serv. 2008;44(1):26-9. (not federally funded)
• Olives C, Pagano M, Deitchler M, Hedt BL, Egge K and Valadez JJ. Cluster designs to assess the prevalence of acute malnutrition by lot quality assurance sampling: a validation study by computer simulation. J R Stat Soc Ser A Stat Soc. 2009 Apr;172(2):495-510. PMCID: PMC2784900
• Ahmed HM, Mitchell M and Hedt B. National implementation of Integrated Management of Childhood Illness (IMCI): policy constraints and strategies. Health Policy. 2010 Jul;96(2):128-33. (Review)
• Biedron C, Pagano M, Hedt BL, Kilian A, Ratcliffe A, Mabunda S and Valadez JJ. An assessment of Lot Quality Assurance Sampling to evaluate malaria outcome indicators: extending malaria indicator surveys. Int J Epidemiol. 2010 Feb;39(1):72-9. PMCID: PMC2912491
• Cohen T, Hedt BL and Pagano M. Estimating the magnitude and direction of bias in tuberculosis drug resistance surveys conducted only in the public sector: a simulation study. BMC Public Health. 2010;10:355. PMCID: PMC2898828
• Hedt BL, Laufer MK and Cohen T. Drug resistance surveillance in resource-poor settings: current methods and considerations for TB, HIV, and malaria. Am J Trop Med Hyg. 2011 Feb;84(2):192-9. PMCID: PMC3029167
• Cohen T, Manjourides J and Hedt-Gauthier B. Linking surveillance with action against drug-resistant tuberculosis. Am J Respir Crit Care Med. 2012 Sep 1;186(5):399-401. PMCID: PMC3443807
• Hedt BL, van Leth F, Zignol M, Cobelens F, van Gemert W, Nhung NV, Lyepshina S, Egwaga S and Cohen T. Multidrug resistance among new tuberculosis cases: detecting local variation through lot quality-assurance sampling. Epidemiology. 2012 Mar;23(2):293-300. PMCID: PMC3276714
• Hedt-Gauthier BL, Tenthani L, Mitchell S, Chimbwandira FM, Makombe S, Chirwa Z, Schouten EJ, Pagano M and Jahn A. Improving data quality and supervision of antiretroviral therapy sites in Malawi: an application of Lot Quality Assurance Sampling. BMC Health Serv Res. 2012;12:196. PMCID: PMC3411464
• Mitchell M, Getchell M, Nkaka M, Msellemu D, Van Esch J and Hedt-Gauthier B. Perceived improvement in integrated management of childhood illness implementation through use of mobile technology: qualitative evidence from a pilot study in Tanzania. J Health Commun. 2012;17 Suppl 1:118-27. (not federally funded)
• Mitchell M, Hedt BL, Eshun-Wilson I, Fraser H, John MA, Menezes C, Grobusch MP, Jackson J, Taljaard J and Lesh N. Electronic decision protocols for ART patient triaging to expand access to HIV treatment in South Africa: a cross sectional study for development and validation. Int J Med Inform. 2012 Mar;81(3):166-72. PMCID: PMC3279573
• Sanguansak T, Morley MG, Yospaiboon Y, Lorch A, Hedt B and Morley K. The impact of preprinted prescription forms on medication prescribing errors in an ophthalmology clinic in northeast Thailand: a non- randomised interventional study. BMJ Open. 2012;2:e000539. PMCID: PMC3289984
• Satti H, McLaughlin MM, Hedt-Gauthier B, Atwood SS, Omotayo DB, Ntlamelle L and Seung KJ. Outcomes of multidrug-resistant tuberculosis treatment with early initiation of antiretroviral therapy for HIV co-infected patients in Lesotho. PLoS One. 2012;7(10):e46943. PMCID: PMC3480376
• Wadonda-Kabondo N, Hedt BL, van Oosterhout JJ, Moyo K, Limbambala E, Bello G, Chilima B, Schouten E, Harries A, Massaquoi M, Porter C, Weigel R, Hosseinipour M, Aberle-Grasse J, Jordan MR, Kabuluzi S and Bennett DE. A retrospective survey of HIV drug resistance among patients 1 year after initiation of antiretroviral therapy at 4 clinics in Malawi. Clin Infect Dis. 2012 May;54 Suppl 4:S355-61. PMCID: PMC3338311
• Admon AJ, Bazile J, Makungwa H, Chingoli MA, Hirschhorn LR, Peckarsky M, Rigodon J, Herce M, Chingoli F, Malani N and Hedt-Gauthier BL. Assessing and improving data quality from community health workers: a successful intervention in Neno, Malawi. Public Health Action. 2013;3(1):56-9. (not federally funded)
• Mitsunaga T, Hedt-Gauthier B, Ngizwenayo E, Farmer DB, Karamaga A, Drobac P, Basinga P, Hirschhorn L, Ngabo F and Mugeni C. Utilizing community health worker data for program management and evaluation: systems for data quality assessments and baseline results from Rwanda. Soc Sci Med. 2013 May;85:87-92. (not federally funded)
• Mitchell M, Hedt-Gauthier BL, Msellemu D, Nkaka M and Lesh N. Using electronic technology to improve clinical care — results from a before-after cluster trial to evaluate assessment and classification of sick children according to Integrated Management of Childhood Illness (IMCI) protocol in Tanzania. BMC Med Inform Decis Mak. 2013 Aug 27;13(1):95. PMCID: PMC3766002
• Hedt-Gauthier BL, Mitsunaga T, Hund L, Olives C and Pagano M. The effect of clustering on lot quality assurance sampling: a probabilistic model to calculate sample sizes for quality assessments. Emerg Themes Epidemiol. 2013 Oct 26 [Epub ahead of print];10(1):11. PMCID:PMC3819670
• Mitchell S, Ozonoff A, Zaslavsky AM, Hedt-Gauthier B, Lum K and Coull BA. A comparison of marginal and conditional models for capture-recapture data with application to human rights violations data. Biometrics. 2013 Oct 25 [Epub ahead of print].
• Vasan A, Anatole M, Mezzacappa C, Hedt-Gauthier BL, Hirschhorn LR, Nkikabahizi F, Hagenimana M, Ndayisaba A, Cyamatare FR, Nzeyimana B, Drobac P, Gupta N. Baseline assessment of adult and adolescent primary care delivery in Rwanda: an opportunity for quality improvement. BMC Health Serv Res. 2013 Dec 17;13(1):518. doi: 10.1186/1472-6963-13-518. PMCID:PMC3878570

Caitlin Ravichandran (2002-2007)
Current Position: Instructor of Psychiatry/Assistant Biostatistician Program for Neuropsychiatric Research, McLean Hospital/Harvard Medical School

Publications while in training include:

• Buka SL, Goldstein JM, Seidman LJ, Thomas C, Denny LR, Horton NJ and Tsuang MT. Risk of obstetrical complications in offspring of parents with schizophrenia. Schizophrenia Research, 2002; 53(3): 243-243.
• Unaeze J, Nijsten T, Murphy A, Ravichandran Cand Stern RS. Impact of psoriasis on health-related quality of life decreases over time: An 11-year prospective study. Journal of Investigative Dermatology, 2006; 126: 1480-1489.
• Fitzmaurice GM and Ravichandran C. A primer in longitudinal data analysis. Circulation. 2008 Nov 4;118(19):2005-10. Comment.
• Ravichandran C and Fitzmaurice GM. To dichotomize or not to dichotomize? Nutrition. 2008 Jun;24(6):610-1. (accepted for publication prior to April 7, 2008)
• Ravichandran C and Fitzmaurice GM. A tale of two nutritionists (or the importance of analysis plans). Nutrition. 2008 Nov-Dec;24(11-12):1227-8. (accepted for publication prior to April 7, 2008)
• Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH and Hamblin MR. Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety. Behav Brain Funct. 2009;5:46. PMCID: PMC2796659
• Fletcher PT, Whitaker RT, Tao R, DuBray MB, Froehlich A, Ravichandran C, Alexander AL, Bigler ED, Lange N and Lainhart JE. Microstructural connectivity of the arcuate fasciculus in adolescents with high-functioning autism. Neuroimage. 2010 Jul 1;51(3):1117-25. PMCID: PMC2966943
• Lange N, Dubray MB, Lee JE, Froimowitz MP, Froehlich A, Adluru N, Wright B, Ravichandran C, Fletcher PT, Bigler ED, Alexander AL and Lainhart JE. Atypical diffusion tensor hemispheric asymmetry in autism. Autism Res. 2010 Dec;3(6):350-8. PMCID: PMC3215255
• Anderson JS, Nielsen JA, Froehlich AL, DuBray MB, Druzgal TJ, Cariello AN, Cooperrider JR, Zielinski BA, Ravichandran C, Fletcher PT, Alexander AL, Bigler ED, Lange N and Lainhart JE. Functional connectivity magnetic resonance imaging classification of autism. Brain. 2011 Dec;134(Pt 12):3742-54. PMCID: PMC3235557
• Licata SC, Penetar DM, Ravichandran C, Rodolico J, Palmer C, Berko J, Geaghan T, Looby A, Peters E, Ryan E, Renshaw PF and Lukas SE. Effects of daily treatment with citicoline: a double-blind, placebo- controlled study in cocaine-dependent volunteers. J Addict Med. 2011 Mar;5(1):57-64. PMCID: PMC3140015
• Nickerson LD, Ravichandran C, Lundahl LH, Rodolico J, Dunlap S, Trksak GH and Lukas SE. Cue reactivity in cannabis-dependent adolescents. Psychol Addict Behav. 2011 Mar;25(1):168-73. PMCID: PMC3066287
• Potuzak M, Ravichandran C, Lewandowski KE, Ongur D and Cohen BM. Categorical vs dimensional classifications of psychotic disorders. Compr Psychiatry. 2012 Nov;53(8):1118-29. PMCID: PMC3488145
• Progress Report Page 84Contact PD/PI: Pagano, Marcello
• Harper DG, Jensen JE, Ravichandran C, Sivrioglu Y, Silveri M, Iosifescu DV, Renshaw PF and Forester BP. Tissue-Specific Differences in Brain Phosphodiesters in Late-Life Major Depression. Am J Geriatr Psychiatry. 2013 Jan 11. PMCID: PMC3749264 [Available on 2014/7/11]
• Harper DG, Plante DT, Jensen JE, Ravichandran C, Buxton OM, Benson KL, O’Connor SP, Renshaw PF and Winkelman JW. Energetic and cell membrane metabolic products in patients with primary insomnia: a 31- phosphorus magnetic resonance spectroscopy study at 4 tesla. Sleep. 2013 Apr;36(4):493-500. PMCID: PMC3612248
• Prigge MB, Lange N, Bigler ED, Merkley TL, Neeley ES, Abildskov TJ, Froehlich AL, Nielsen JA, Cooperrider JR, Cariello AN, Ravichandran C, Alexander AL and Lainhart JE. Corpus Callosum Area in Children and Adults with Autism. Res Autism Spectr Disord. 2013;7(2):221-34. PMCID: PMC3487714 [Available on 2014/1/1]
• Prigge MD, Bigler ED, Fletcher PT, Zielinski BA, Ravichandran C, Anderson J, Froehlich A, Abildskov T, Papadopolous E, Maasberg K, Nielsen JA, Alexander AL, Lange N and Lainhart J. Longitudinal Heschl’s gyrus growth during childhood and adolescence in typical development and autism. Autism Res. 2013 Apr;6(2):78- 90. PMCID: PMC3669648 [Available on 2014/4/1]
• Harper DG, Plante DT, Jensen JE, Ravichandran C, Buxton OM, Benson KL, O’Connor SP, Renshaw PF, Winkelman JW. Energetic and cell membrane metabolic products in patients with primary insomnia: a 31- phosphorus magnetic resonance spectroscopy study at 4 tesla. Sleep. 2013 Apr 1;36(4):493-500. doi: 10.5665/sleep.2530. PMCID: PMC3612248

Brian Healy (2002-2007)
Current Position: Assistant Professor of Neurology, Brigham & Women’s Hospital and Harvard Medical School

Publications while in training include:

• Barratt BJ, Payne F, Lowe CE, Hermann R, Healy BC, Harold D, Concannon P, Gharani N, McCarthy MI, Olavesen MG, McCormack R, Guja C, Ionescu-Tirgoviste C, Undlien DE, Ronningen KS, Gillespie KM, Tuomilehto-Wolf E, Tuomilehto J, Bennett ST, Clayton DG, Cordell HJ and Todd JA. Remapping the insulin gene/IDDM2 locus in type 1 diabetes. Diabetes, 2004; 53(7): 1884-9.
• Burren OS, Healy BC, Lam AC, Schuilenburg H, Dolman GE, Everett VH, Laneri D, Nutland S, Rance HE, Payne F, Smyth D, Lowe C, Barratt BJ, Twells RC, Rainbow DB, Wicker LS, Todd JA, Walker NM and Smink LJ. Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics. Hum Genomics, 2004; 1(2): 98-109.
• Smink LJ, Helton EM, Healy BC, Cavnor CC, Lam AC, Flamez D, Burren OS, Wang Y, Dolman GE, Burdick DB, Everett VH, Glusman G, Laneri D, Rowen L, Schuilenburg H, Walker NM, Mychaleckyj J, Wicker LS, Eizirik DL, Todd JA and Goodman N. T1DBase, a community web-based resource for type 1 diabetes research. Nucleic Acids Res, 2005; 33(Database issue): D544-9.
• Wicker LS, Clark J, Fraser HI, Garner VE, Gonzalez-Munoz A, Healy B, Howlett S, Hunter K, Rainbow D, Rosa RL, Smink LJ, Todd JA and Peterson LB. Type 1 diabetes genes and pathways shared by humans and NOD mice. J Autoimmun, 2005; 25 Suppl: 29-33.
• Wicker LS, Moule CL, Fraser H, Penha-Goncalves C, Rainbow D, Garner VE, Chamberlain G, Hunter K, Howlett S, Clark J, Gonzalez-Munoz A, Cumiskey AM, Tiffen P, Howson J, Healy B, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA and Peterson LB. Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse. Novartis Found Symp, 2005; 267: 57-65; discussion 65-75.
• Abdel-Wahab OI, Healy Band Dzik WH. Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities. Transfusion, 2006; 46(8): 1279-85.
• Healy B, Llewelyn M, Westmoreland D, Lloyd G and Brown N. The value of follow-up after acute Q fever infection. J Infect, 2006; 52(4): e109-12.
• Morris GA, Lowe CE, Cooper JD, Payne F, Vella A, Godfrey L, Hulme JS, Walker NM, Healy BC, Lam AC, Lyons PA and Todd JA. Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes. BMC Genet, 2006; 7: 12.
• Taniguchi H, Lowe CE, Cooper JD, Smyth DJ, Bailey R, Nutland S, Healy BC, Lam AC, Burren O, Walker NM, Smink LJ, Wicker LS and Todd JA. Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes. BMC Genet, 2006; 7: 22.
• Wren TA, Do KP, Rethlefsen SA and Healy B. Cross-correlation as a method for comparing dynamic electromyography signals during gait. J Biomech, 2006; 39(14): 2714-8.
• Finlay EK, Gaillard C, Vahidi SM, Mirhoseini SZ, Jianlin H, Qi XB, El-Barody MA, Baird JF, Healy BCand Bradley DG. Bayesian inference of population expansions in domestic bovines. Biol Lett, 2007; 3(4): 449-52.
• Healy B, De Gruttola V and Pagano M. Combining cross-sectional and prospective data methods to improve transition parameter estimation for characterizing the accumulation of HIV-1 drug resistance mutations. Biometrics, 2007; 63(3): 742-50.
• Healy Band Degruttola V. Hidden Markov models for settings with interval-censored transition times and uncertain time origin: application to HIV genetic analyses. Biostatistics, 2007; 8(2): 438-52.
• Hulbert EM, Smink LJ, Adlem EC, Allen JE, Burdick DB, Burren OS, Cassen VM, Cavnor CC, Dolman GE, Flamez D, Friery KF, Healy BC, Killcoyne SA, Kutlu B, Schuilenburg H, Walker NM, Mychaleckyj J, Eizirik DL, Wicker LS, Todd JA and Goodman N. T1DBase: integration and presentation of complex data for type 1 diabetes research. Nucleic Acids Res, 2007; 35(Database issue): D742-6.
• Ridgway WM, Healy B, Smink LJ, Rainbow D and Wicker LS. New tools for defining the ‘genetic background’ of inbred mouse strains. Nat Immunol, 2007; 8(7): 669-73.
• Szeszko JS, Healy B, Stevens H, Balabanova Y, Drobniewski F, Todd JA and Nejentsev S. Resequencing and association analysis of the SP110 gene in adult pulmonary tuberculosis. Hum Genet, 2007; 121(2): 155-60.
• Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tirgoviste C, Simmonds MJ, Heward JM, Gough SC, Dunger DB, Wicker LS and Clayton DG. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet, 2007; 39(7): 857-64.
• Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS and Santamaria P. Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet, 2007; 39(3): 329-37.
• Healy B, Guttmann C, Sampat M, Weiner H, Hafler D and De Jager P. Alleles in the OLIG gene locus affect the rate of brain atrophy in multiple sclerosis. Neurology, 2008; 70(11): A394-A394.
• Healy BC, DeGruttola VG and Hu C. Accommodating uncertainty in a tree set for function estimation. Stat Appl Genet Mol Biol, 2008; 7: Article5.
• Kivisakk P, Viglietta V, Healy B, Weiner H and Khoury S. A panel of immunologic biomarkers can discriminate between patients with multiple sclerosis and healthy individuals. Clinical Immunology, 2008; 127: S50-S50.
• Neema M, Arora A, Healy B, Guss ZD, Brass S, Duan Y, Buckle G, Glanz B, Stazzone L, Khoury S, Weiner H, Guttmann C and Bakshi R. Gray matter damage on brain MRI scans is associated with clinical progression in multiple sclerosis. Neurology, 2008; 70(11): A431-A431.
• Sampat MP, Sander C, Berger A, Healy B, Felsovalyi OL, Hildenbrand P, Meier D, Khoury S, Bakshi R, Weiner H and Guttmann C. Discriminant analysis of US subtypes through readily obtainable regional atrophy metrics. Neurology, 2008; 70(11): A464-A464.
• Stankiewicz JM, Glanz B, Healy B, Benedict R, Arora A, Neema M, Guss ZD, Buckle G, Houtchens M, Khoury S, Weiner H, Guttmann C and Bakshi R. Brain MRI lesion volume correlates with physical disability and cognitive impairment in multiple sclerosis: Comparison of 1.5T and 3T. Neurology. 2008 Mar;70(11):A473-A. Stankiewicz JM, Neema M, Alsop DC, Healy B, Arora A, Buckle GJ, Chitnis T, Guttmann CRG, Hackney D and Bakshi R. Whole spinal cord lesion detection with 1.5T and 3T MRI and clinical correlation in patients with multiple sclerosis. Neurology. 2008 Mar;70(11):A473-A.
• Gorman MP, Healy BC, Polgar-Turcsanyi M and Chitnis T. Increased relapse rate in pediatric-onset compared with adult-onset multiple sclerosis. Arch Neurol. 2009 Jan;66(1):54-9. (not federally funded)
• Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H and Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul;66(7):858-64. PMCID: PMC2754172
• Healy BC and Engler D. Modeling disease-state transition heterogeneity through Bayesian variable selection. Stat Med. 2009 Apr 30;28(9):1353-68. (not federally funded)
• Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y, Buckle GJ, Glanz BI, Stazzone L, Khoury SJ, Weiner HL, Guttmann CR and Bakshi R. Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. J Neuroimaging. 2009 Jan;19(1):3-8. PMCID: PMC2762230
• Neema M, Goldberg-Zimring D, Guss ZD, Healy BC, Guttmann CR, Houtchens MK, Weiner HL, Horsfield MA, Hackney DB, Alsop DC and Bakshi R. 3 T MRI relaxometry detects T2 prolongation in the cerebral normal- appearing white matter in multiple sclerosis. Neuroimage. 2009 Jul 1;46(3):633-41. PMCID: PMC2974316
• Neema M, Guss ZD, Stankiewicz JM, Arora A, Healy BC and Bakshi R. Normal findings on brain fluid- attenuated inversion recovery MR images at 3T. AJNR Am J Neuroradiol. 2009 May;30(5):911-6. PMCID: PMC3003332
• Sampat MP, Berger AM, Healy BC, Hildenbrand P, Vass J, Meier DS, Chitnis T, Weiner HL, Bakshi R and Guttmann CR. Regional white matter atrophy–based classification of multiple sclerosis in cross-sectional and longitudinal data. AJNR Am J Neuroradiol. 2009 Oct;30(9):1731-9. PMCID: PMC2821733
• Glanz BI, Healy BC, Rintell DJ, Jaffin SK, Bakshi R and Weiner HL. The association between cognitive impairment and quality of life in patients with early multiple sclerosis. J Neurol Sci. 2010 Mar 15;290(1-2):75-9. (not federally funded)
• Healy BC, Glanz BI, Stankiewicz J, Buckle G, Weiner H and Chitnis T. A method for evaluating treatment switching criteria in multiple sclerosis. Mult Scler. 2010 Dec;16(12):1483-9. (not federally funded)
• Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR and De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17;75(7):634- 40. PMCID: PMC2931768
• Khoury SJ, Healy BC, Kivisakk P, Viglietta V, Egorova S, Guttmann CR, Wedgwood JF, Hafler DA, Weiner HL, Buckle G, Cook S and Reddy S. A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis. Arch Neurol. 2010 Sep;67(9):1055-61. PMCID: PMC2954052
• Meier DS, Balashov KE, Healy B, Weiner HL and Guttmann CR. Seasonal prevalence of MS disease activity. Neurology. 2010 Aug 31;75(9):799-806. PMCID: PMC2938966
• Vishwas MS, Chitnis T, Pienaar R, Healy BC and Grant PE. Tract-based analysis of callosal, projection, and association pathways in pediatric patients with multiple sclerosis: a preliminary study. AJNR Am J Neuroradiol. 2010 Jan;31(1):121-8.(not federally funded)
• Gholipour T, Healy B, Baruch NF, Weiner HL and Chitnis T. Demographic and clinical characteristics of malignant multiple sclerosis. Neurology. 2011 Jun 7;76(23):1996-2001. (not federally funded)
• Healy BC, Engler D, Gholipour T, Weiner H, Bakshi R and Chitnis T. Accounting for disease modifying therapy in models of clinical progression in multiple sclerosis. J Neurol Sci. 2011 Apr 15;303(1-2):109-13. (not federally funded)
• Healy B, Chitnis T, Engler D. Improving power to detect disease progression in multiple sclerosis through alternative analysis strategies. J Neurol. 2011 Oct;258(10):1812-9. doi: 10.1007/s00415-011-6021-1. Epub 2011 Apr 7. (not federally funded)
• Huffman JC, Mastromauro CA, Sowden G, Fricchione GL, Healy BC and Januzzi JL. Impact of a depression care management program for hospitalized cardiac patients. Circ Cardiovasc Qual Outcomes. 2011 Mar;4(2):198-205. (not federally funded)
• Klein JP, Arora A, Neema M, Healy BC, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Stankiewicz JM, Cohen AB, Buckle GJ, Houtchens MK, Ceccarelli A, Dell’Oglio E, Guttmann CR, Alsop DC, Hackney DB and Bakshi R. A 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2011 Jun-Jul;32(6):1138-42. PMCID: PMC3361764
• Moscufo N, Guttmann CR, Meier D, Csapo I, Hildenbrand PG, Healy BC, Schmidt JA and Wolfson L. Brain regional lesion burden and impaired mobility in the elderly. Neurobiol Aging. 2011 Apr;32(4):646-54. PMCID: PMC2942957
• Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR and Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr;21(2):e50-6. PMCID: PMC3043123
• Xiao D, Cassin JJ, Healy B, Burdett TC, Chen JF, Fredholm BB and Schwarzschild MA. Deletion of adenosine A(1) or A((2)A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson’s disease. Brain Res. 2011 Jan 7;1367:310-8. PMCID: PMC3005012
• Glanz BI, Healy BC, Hviid LE, Chitnis T and Weiner HL. Cognitive deterioration in patients with early multiple sclerosis: a 5-year study. J Neurol Neurosurg Psychiatry. 2012 Jan;83(1):38-43. (not federally funded)
• Healy BC, Arora A, Hayden DL, Ceccarelli A, Tauhid SS, Neema M and Bakshi R. Approaches to normalization of spinal cord volume: application to multiple sclerosis. J Neuroimaging. 2012 Jul;22(3):e12-9. PMCID: PMC3290735
• Healy BC, Degano IR, Schreck A, Rintell D, Weiner H, Chitnis T and Glanz BI. The impact of a recent relapse on patient-reported outcomes in subjects with multiple sclerosis. Qual Life Res. 2012 Dec;21(10):1677-84. (not federally funded)
• Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M and Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15;315(1-2):49-54. PMCID: PMC3319060
• Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL and Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013;13:73. PMCID: PMC3707791
• Bove R, Secor E, Healy BC, Musallam A, Vaughan T, Glanz BI, Greeke E, Weiner HL, Chitnis T, Wicks P and De Jager PL. Evaluation of an online platform for multiple sclerosis research: patient description, validation of severity scale, and exploration of BMI effects on disease course. PLoS One. 2013;8(3):e59707. PMCID: PMC3603866
• Healy BC, Engler D, Glanz B, Musallam A and Chitnis T. Assessment of definitions of sustained disease progression in relapsing-remitting multiple sclerosis. Mult Scler Int. 2013;2013:189624. PMCID: PMC3608311
• Schwartz CE, Quaranto BR, Healy BC, Benedict RH and Vollmer TL. Cognitive reserve and symptom experience in multiple sclerosis: a buffer to disability progression over time? Arch Phys Med Rehabil. 2013 Oct;94(10):1971-81 e1 (not federally funded).
• Messina S, Vargas-Lowy D, Musallam A, Healy B, Healy BC, Gandhi R, Bove R, Gholipour T, Khoury S, Weiner HL, Chitnis T. Increased leptin and A-FABP levels in relapsing and progressive forms of MS. BMC Neurol. 2013 Nov 11;13(1):172. [Epub ahead of print] PMCID:PMC3829106
• Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttmann B, Yeh A, Rodriguez M, Ness J, Gorman M, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B,
• Bergsland N, Zivadinov R. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC Neurol. 2013 Nov 13;13(1):173. [Epub ahead of print] PMCID:PMC3832402

Stacia DeSantis (2002-2007)
Current Position: Associate Professor, Division of Biostatistics, University of Texas Medical Center

Publications while in training include:

• DeSantis SM, Pau CP, Archibald LK, Nwanyanwu OC, Kazembe PN, Dobbie H, Jarvis WR and Jason J. Demographic and immune correlates of human herpesvirus 8 seropositivity in Malawi, Africa. Int J Infect Dis. 2002 Dec;6(4):266-71.
• Quiroz R, Gerhard-Herman M, Kosowsky JM, DeSantis SM, Kucher N, McKean SC and Goldhaber SZ. Comparison of a single end point to determine optimal initial warfarin dosing (5 mg versus 10 mg) for venous thromboembolism. The American journal of cardiology. 2006 Aug 15;98(4):535-7.
• Desantis SM, Houseman EA, Coull BA, Stemmer-Rachamimov A and Betensky RA. A penalized latent class model for ordinal data. Biostatistics, 2008; 9(2): 249-62.
• Palmieri G, Acone F, Desantis S, Corriero A, Ventriglia G, Addis P, Genovese S, Aprea A, Spedicato D, Losurdo M, Deflorio M, Di Summa A and De Metrio G. Brain morphology and immunohistochemical localization of the gonadotropin-releasing hormone in the bluefin tuna, Thunnus thynnus. European Journal of Histochemistry, 2008; 52(1): 19-27.
• Snuderl M, Chi SN, DeSantis S, Stemmer-Rachamimov A, Betensky RA, DeGirolami U and Kieran MW. Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas. Journal of Neuropathology and Experimental Neurology, 2008; 67(5): 502-502.
• Brady KT, McRae AL, Moran-Santa Maria MM, DeSantis SM, Simpson AN, Waldrop AE, Back SE and Kreek MJ. Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals. Arch Gen Psychiatry. 2009 Apr;66(4):422-30. PMCID: PMC2696287
• Carpenter MJ, Saladin ME, DeSantis S, Gray KM, LaRowe SD and Upadhyaya HP. Laboratory-based, cue- elicited craving and cue reactivity as predictors of naturally occurring smoking behavior. Addict Behav. 2009 Jun-Jul;34(6-7):536-41. PMCID: PMC2685198
• DeSantis SM, Bandyopadhyay D, Back SE and Brady KT. Non-treatment laboratory stress- and cue-reactivity studies are associated with decreased substance use among drug-dependent individuals. Drug Alcohol Depend. 2009 Dec 1;105(3):227-33. PMCID: PMC2875261
• DeSantis SM, Houseman EA, Coull BA, Louis DN, Mohapatra G and Betensky RA. A latent class model with hidden Markov dependence for array CGH data. Biometrics. 2009 Dec;65(4):1296-305. PMCID: PMC3052263
• Price KL, McRae-Clark AL, Saladin ME, Maria MM, DeSantis SM, Back SE and Brady KT. D-cycloserine and cocaine cue reactivity: preliminary findings. Am J Drug Alcohol Abuse. 2009;35(6):434-8. PMCID: PMC2805418
• Back SE, Hartwell K, DeSantis SM, Saladin M, McRae-Clark AL, Price KL, Moran-Santa Maria MM, Baker NL, Spratt E, Kreek MJ and Brady KT. Reactivity to laboratory stress provocation predicts relapse to cocaine. Drug Alcohol Depend. 2010 Jan 1;106(1):21-7. PMCID: PMC2815094
• Gray KM, DeSantis SM, Carpenter MJ, Saladin ME, LaRowe SD and Upadhyaya HP. Menstrual cycle and cue reactivity in women smokers. Nicotine Tob Res. 2010 Feb;12(2):174-8. PMCID: PMC2816193
• McQuinn TC, Deardorff RL, Mukherjee R, Taylor AG, Graham EM, Atz AM, Forbus GA, DeSantis SM, Young JB, Stroud RE, Crawford FA, Bradley SM, Reeves ST and Spinale FG. Circulating matrix metalloproteinase levels after ventricular septal defect repair in infants. J Thorac Cardiovasc Surg. 2010 Dec;140(6):1257-65. PMCID: PMC2972374
• Moran-Santa Maria MM, McRae-Clark AL, Back SE, DeSantis SM, Baker NL, Spratt EG, Simpson AN and Brady KT. Influence of cocaine dependence and early life stress on pituitary-adrenal axis responses to CRH and the Trier social stressor. Psychoneuroendocrinology. 2010 Nov;35(10):1492-500. PMCID: PMC2945624
• Price KL, Saladin ME, Baker NL, Tolliver BK, DeSantis SM, McRae-Clark AL and Brady KT. Extinction of drug cue reactivity in methamphetamine-dependent individuals. Behav Res Ther. 2010 Sep;48(9):860-5. PMCID: PMC2914141
• Waldrop AE, Price KL, DeSantis SM, Simpson AN, Back SE, McRae AL, Spratt EG, Kreek MJ and Brady KT. Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues. Psychoneuroendocrinology. 2010 Jul;35(6):798-806. PMCID: PMC2875320
• Bandyopadhyay D, DeSantis SM, Korte JE and Brady KT. Some considerations for excess zeroes in substance abuse research. Am J Drug Alcohol Abuse. 2011 Sep;37(5):376-82. PMCID: PMC3297079
• DeSantis SM, Baker NL, Back SE, Spratt E, Ciolino JD, Moran-Santa Maria M, Dipankar B and Brady KT. Gender differences in the effect of early life trauma on hypothalamic-pituitary-adrenal axis functioning. Depress Anxiety. 2011 May;28(5):383-92. PMCID: PMC3243643
• DeSantis SM and Bandyopadhyay D. Hidden Markov models for zero-inflated Poisson counts with an application to substance use. Stat Med. 2011 Jun 30;30(14):1678-94. PMCID: PMC3248646
• DeSantis SM, Toole JM, Kratz JM, Uber WE, Wheat MJ, Stroud MR, Ikonomidis JS and Spinale FG. Early postoperative outcomes and blood product utilization in adult cardiac surgery: the post-aprotinin era. Circulation. 2011 Sep 13;124(11 Suppl):S62-9. PMCID: PMC3181091
• Graham EM, Atz AM, Butts RJ, Baker NL, Zyblewski SC, Deardorff RL, DeSantis SM, Reeves ST, Bradley SM and Spinale FG. Standardized preoperative corticosteroid treatment in neonates undergoing cardiac surgery: results from a randomized trial. J Thorac Cardiovasc Surg. 2011 Dec;142(6):1523-9. PMCID: PMC3161127
• Price KL, DeSantis SM, Simpson AN, Tolliver BK, McRae-Clark AL, Saladin ME, Baker NL, Wagner MT and Brady KT. The impact of clinical and demographic variables on cognitive performance in methamphetamine- dependent individuals in rural South Carolina. Am J Addict. 2011 Sep-Oct;20(5):447-55. PMCID: PMC3603567
• Zile MR, Mehurg SM, Arroyo JE, Stroud RE, DeSantis SM and Spinale FG. Relationship between the temporal profile of plasma microRNA and left ventricular remodeling in patients after myocardial infarction. Circ Cardiovasc Genet. 2011 Dec;4(6):614-9. PMCID: PMC3535326
• DeSantis SM, Houseman EA, Coull BA, Nutt CL and Betensky RA. Supervised Bayesian latent class models for high-dimensional data. Stat Med. 2012 Jun 15;31(13):1342-60. PMCID: PMC3701307
• Graham EM, Atz AM, Gillis J, DeSantis SM, Haney AL, Deardorff RL, Uber WE, Reeves ST, McGowan FX, Jr., Bradley SM and Spinale FG. Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2012 May;143(5):1069-76. PMCID: PMC3349086
• Gray KM, Carpenter MJ, Baker NL, DeSantis SM, Kryway E, Hartwell KJ, McRae-Clark AL and Brady KT. A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents. Am J Psychiatry. 2012 Aug 1;169(8):805-12. PMCID: PMC3410961
• Prisciandaro JJ, DeSantis SM and Bandyopadhyay D. Simultaneous modeling of the impact of treatments on alcohol consumption and quality of life in the COMBINE study: a coupled hidden Markov analysis. Alcohol Clin Exp Res. 2012 Dec;36(12):2141-9. PMCID: PMC3416970 [Available on 2013/12/1]
• Prisciandaro JJ, DeSantis SM, Chiuzan C, Brown DG, Brady KT and Tolliver BK. Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate. Alcohol Clin Exp Res. 2012 Mar;36(3):490-6. PMCID: PMC3248624
• Saladin ME, Gray KM, Carpenter MJ, LaRowe SD, DeSantis SM and Upadhyaya HP. Gender differences in craving and cue reactivity to smoking and negative affect/stress cues. Am J Addict. 2012 May-Jun;21(3):210- 20. PMCID: PMC3325498
• Hartwell KJ, Moran-Santa Maria MM, Twal WO, Shaftman S, DeSantis SM, McRae-Clark AL and Brady KT. Association of elevated cytokines with childhood adversity in a sample of healthy adults. J Psychiatr Res. 2013 May;47(5):604-10. PMCID: PMC3594625 [Available on 2014/5/1]
• Lazaridis C, Neyens R, Bodle J and DeSantis SM. High-osmolarity saline in neurocritical care: systematic review and meta-analysis. Crit Care Med. 2013 May;41(5):1353-60. Comment.
• Price KL, Baker NL, McRae-Clark AL, Saladin ME, DeSantis SM, Santa Ana EJ and Brady KT. A randomized, placebo-controlled laboratory study of the effects of D-cycloserine on craving in cocaine-dependent individuals. Psychopharmacology (Berl). 2013 Apr;226(4):739-46. PMCID: PMC3622147 [Available on 2014/4/1]
• Sequeira KM, Tabesh A, Sainju RK, DeSantis SM, Naselaris T, Joseph JE, Ahlman MA, Spicer KM, Glazier SS, Edwards JC and Bonilha L. Perfusion network shift during seizures in medial temporal lobe epilepsy. PLoS One. 2013;8(1):e53204. PMCID: PMC3544909
• DeSantis SM, Lazaridis C, Ji S, Spinale FG. Analyzing Propensity Matched Zero-Inflated Count Outcomes in Observational Studies. J Appl Stat. 2014 Jan 1;41(1). doi: 10.1080/02664763.2013.834296. PMCID: PMC3843491

Laura Forsberg White (2001-2006)
Current Position: Adjunct Associate Professor of Biostatistics, Harvard T. H. Chan School of Public Health

Publications while in training include:

• Ozonoff A, Bonetti M, Forsberg Land Pagano M. Power comparisons for an improved disease clustering test. Computational Statistics & Data Analysis, 2005; 48(4): 679-684.
• Ozonoff A, Jeffery C, Manjourides J, White LFand Pagano M. Effect of spatial resolution on cluster detection: a simulation study. International Journal of Health Geographics, 2007; 6.
• Coogan PF, White LF, Palmer JR and Rosenberg L. The influence of urban form on walking in the black women’s health study. American Journal of Epidemiology, 2008; 167(11): S103-S103.
• White LF and Pagano M. A likelihood-based method for real-time estimation of the serial interval and reproductive number of an epidemic. Statistics in Medicine. 2008 Jul;27(16):2999-3016. Article first published online: 3 DEC 2007
• Chartrand MM, Frank DA, White LF, Shope TR. Effect of parents’ wartime deployment on the behavior of young children in military families. Arch Pediatr Adolesc Med. 2008 Nov;162(11):1009-14. doi:10.1001/archpedi.162.11.1009. (not federally funded)
• White LF and Pagano M. Transmissibility of the influenza virus in the 1918 pandemic. PLoS One. 2008;3(1):e1498. PMCID: PMC2204055
• Jeffery C, Ozonoff A, White LF, Nuño M, Pagano M. Power to detect spatial disturbances under different levels of geographic aggregation. J Am Med Inform Assoc. 2009 Nov-Dec;16(6):847-54. doi: 10.1197/jamia.M2788. Epub 2009 Aug 28. PMCID:PMC3002119
• White LF, Bonetti M and Pagano M. The Choice of the Number of Bins for the M Statistic. Comput Stat Data Anal. 2009 Aug 1;53(10):3640-9. PMCID: PMC2703493
• White LF, Wallinga J, Finelli L, Reed C, Riley S, Lipsitch M and Pagano M. Estimation of the reproductive number and the serial interval in early phase of the 2009 influenza A/H1N1 pandemic in the USA. Influenza Other Respi Viruses. 2009 Nov;3(6):267-76. PMCID: PMC2782458
• White LF, Pagano M. Reporting errors in infectious disease outbreaks, with an application to Pandemic Influenza A/H1N1. Epidemiol Perspect Innov. 2010 Dec 15;7:12. doi: 10.1186/1742-5573-7-12. PMCID: PMC3018365
• Coogan PF, White LF, Evans SR, Adler TJ, Hathaway KM, Palmer JR, Rosenberg L. Longitudinal assessment of urban form and weight gain in African-American women. Am J Prev Med. 2011 Apr;40(4):411-8. doi: 10.1016/j.amepre.2010.12.013. PMCID:PMC3059803
• Lipsitch M, Finelli L, Heffernan RT, Leung GM, Redd SC; 2009 H1n1 Surveillance Group (incl. White LF). Improving the evidence base for decision making during a pandemic: the example of 2009 influenza A/H1N1. Biosecur Bioterror. 2011 Jun;9(2):89-115. doi: 10.1089/bsp.2011.0007. PMCID:PMC3102310
• Coogan PF, White LF, Evans SR, Palmer JR, Rosenberg L. The influence of neighborhood socioeconomic status and walkability on TV viewing time. J Phys Act Health. 2012 Nov;9(8):1074-9. Epub 2011 Dec 27. PMCID:PMC3786398
• Coogan PF, White LF, Jerrett M, Brook RD, Su JG, Seto E, Burnett R, Palmer JR, Rosenberg L. Air pollution and incidence of hypertension and diabetes mellitus in black women living in Los Angeles. Circulation. 2012 Feb 14;125(6):767-72. doi: 10.1161/CIRCULATIONAHA.111.052753. Epub 2012 Jan 4. PMCID:PMC3326581
• Archer BN, Tempia S, White LF, Pagano M, Cohen C. Reproductive Number and Serial Interval of the First Wave of Influenza A(H1N1)pdm09 Virus in South Africa. PLoS One. 2012; 7(11):e49482. PMCID:PMC3500305
• Bethea TN, Lopez RP, Cozier YC, White LF, McClean MD. The relationship between rural status, individual characteristics, and self-rated health in the behavioral risk factor surveillance system. J Rural Health. 2012 Sep; 28(4):327-38. PMCID:PMC3481191
• Rathlev NK, Obendorfer D, White LF, Rebholz C, Magauran B, Baker W, Ulrich A, Fisher L, Olshaker J. Time series analysis of emergency department length of stay per 8-hour shift. West J Emerg Med. 2012 May; 13(2):163-8. PMCID:PMC3415804
• White LF, Archer B, Pagano M. Estimating the reproductive number in the presence of spatial heterogeneity of transmission patterns. Int J Health Geogr. 2013; 12(1):35. PMCID:PMC3735474
• Filippelli AC, White LF, Spellman LW, Broderick M, Highfield ES, Sommers E, Gardiner P. Non-Insertive Acupuncture and Neonatal Abstinence Syndrome: A Case Series from an Inner City Safety Net Hospital. Glob Adv Health Med. 2012 Sep;1(4):48-52. PMCID:PMC3783013
• Gardiner P, Mitchell S, Filippelli AC, Sadikova E, White LF, Paasche-Orlow MK, Jack BW. Health literacy and complementary and alternative medicine use among underserved inpatients in a safety net hospital. J Health Commun. 2013;18 Suppl 1:290-7. PMCID:PMC3814611

Katherine Tassiopoulos (2001-2006)
Current Position: Senior Research Scientist, Department of Epidemiology, Harvard T. H. Chan School of Public Health

Publications while in training include:

• Bernstein E, Bernstein J, Tassiopoulos K, Heeren T, Levenson S and Hingson R. Peer educator intervention at the medical visit achieves eduction in cocaine and heroin use. Annals of Emergency Medicine, 2003; 42(4): S45-S45.
• Tassiopoulos K, Bernstein J, Heeren T, Levenson S, Hingson R and Bernstein E. Hair testing and self-report of cocaine use by heroin users. Addiction, 2004; 99(5): 590-597.
• Bernstein E, Bernstein J, Tassiopoulos K, Valentine A, Heeren T, Levenson S and Hingson R. Racial and ethnic diversity among a heroin and cocaine using population: Treatment system utilization. Journal of Addictive Diseases, 2005; 24(4): 43-63.
• Bernstein J, Bernstein E, Tassiopoulos K, Heeren T, Levenson S and Hingson R. Brief motivational intervention at a clinic visit reduces cocaine and heroin use. Drug and Alcohol Dependence, 2005; 77(1): 49-59.
• Tassiopoulos K, Bernstein J, Heeren T, Levenson S, Hingson R and Bernstein E. Predictors of disclosure of continued cocaine use. Addictive Behaviors, 2006; 31(1): 80-89.
• Tassiopoulos KK, Seage GR, Sam NE, Ao TTH, Masenga EJ, Hughes MD and Kapiga SH. Sexual behavior, psychosocial and knowledge differences between consistent, inconsistent and non-users of condoms: A study of female bar and hotel workers in Moshi, Tanzania. AIDS and Behavior, 2006; 10(4): 405-413.
• Tassiopoulos KK, Seage G, Sam N, Kiwelu I, Shao J, Ao TTH, Essex M, Coplan P, Rosenberg Z, Hughes M and Kapiga S. Predictors of Herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania. Journal of Infectious Diseases, 2007; 195(4): 493-501.
• Tassiopoulos K, Williams PL, Seage GR, Crain M, Oleske J and Farley J. Association of hypercholesterolemia incidence with antiretroviral treatment, including protease inhibitors, among perinatally HIV-infected children. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 2008; 47(5): 607-614.
• Tassiopoulos K, Kapiga S, Sam N, Ao TT, Hughes M and Seage GR, 3rd. A case-crossover analysis of predictors of condom use by female bar and hotel workers in Moshi, Tanzania. Int J Epidemiol. 2009 Apr;38(2):552-60. PMCID: PMC2734075
• Brown TT, Tassiopoulos K, Bosch RJ, Shikuma C and McComsey GA. Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy. Diabetes Care. 2010 Oct;33(10):2244-9. PMCID: PMC2945167
• Kapetanovic S, Leister E, Nichols S, Miller T, Tassiopoulos K, Hazra R, Gelbard HA, Malee KM, Kammerer B, Mendez AJ and Williams PL. Relationships between markers of vascular dysfunction and neurodevelopmental outcomes in perinatally HIV-infected youth. AIDS. 2010 Jun 19;24(10):1481-91. PMCID: PMC2885052
• Tassiopoulos K, Read JS, Brogly S, Rich K, Lester B, Spector SA, Yogev R and Seage GR, 3rd. Substance use in HIV-Infected women during pregnancy: self-report versus meconium analysis. AIDS Behav. 2010 Dec;14(6):1269-78. PMCID: PMC3098043
• Mellins CA, Tassiopoulos K, Malee K, Moscicki AB, Patton D, Smith R, Usitalo A, Allison SM, Van Dyke R and Seage GR, 3rd. Behavioral health risks in perinatally HIV-exposed youth: co-occurrence of sexual and drug use behavior, mental health problems, and nonadherence to antiretroviral treatment. AIDS Patient Care STDS. 2011 Jul;25(7):413-22. PMCID: PMC3125549
• Jacobson DL, Williams P, Tassiopoulos K, Melvin A, Hazra R and Farley J. Clinical management and follow- up of hypercholesterolemia among perinatally HIV-infected children enrolled in the PACTG 219C study. J Acquir Immune Defic Syndr. 2011 Aug 15;57(5):413-20. PMCID: PMC3159838
• Malee KM, Tassiopoulos K, Huo Y, Siberry G, Williams PL, Hazra R, Smith RA, Allison SM, Garvie PA, Kammerer B, Kapetanovic S, Nichols S, Van Dyke R, Seage GR, 3rd and Mellins CA. Mental health functioning among children and adolescents with perinatal HIV infection and perinatal HIV exposure. AIDS Care. 2011 Dec;23(12):1533-44. PMCID: PMC3387978
• Crain MJ, Williams PL, Griner R, Tassiopoulos K, Read JS, Mofenson LM and Rich KC. Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications. Pediatr Infect Dis J. 2011 Dec;30(12):1069-74. PMCID: PMC3242409
• Siberry GK, Williams PL, Mendez H, Seage GR, 3rd, Jacobson DL, Hazra R, Rich KC, Griner R, Tassiopoulos K, Kacanek D, Mofenson LM, Miller T, DiMeglio LA and Watts DH. Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants. AIDS. 2012 Jun 1;26(9):1151-9. PMCID: PMC3476702
• Tassiopoulos K, Landay A, Collier AC, Connick E, Deeks SG, Hunt P, Lewis DE, Wilson C and Bosch R. CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies. J Infect Dis. 2012 Jun;205(11):1730-8. PMCID: PMC3415854
• Williams PL, Seage GR, 3rd, Van Dyke RB, Siberry GK, Griner R, Tassiopoulos K, Yildirim C, Read JS, Huo Y, Hazra R, Jacobson DL, Mofenson LM and Rich K. A trigger-based design for evaluating the safety of in utero antiretroviral exposure in uninfected children of human immunodeficiency virus-infected mothers. Am J Epidemiol. 2012 May 1;175(9):950-61. PMCID: PMC3390009
• Yin MT, Kendall MA, Wu X, Tassiopoulos K, Hochberg M, Huang JS, Glesby MJ, Bolivar H and McComsey GA. Fractures after antiretroviral initiation. AIDS. 2012 Nov 13;26(17):2175-84. PMCID: PMC3652631
• Himes SK, Scheidweiler KB, Tassiopoulos K, Kacanek D, Hazra R, Rich K and Huestis MA. Development and validation of the first liquid chromatography-tandem mass spectrometry assay for simultaneous quantification of multiple antiretrovirals in meconium. Anal Chem. 2013 Feb 5;85(3):1896-904. PMCID: PMC3638039
• Tassiopoulos K, Moscicki AB, Mellins C, Kacanek D, Malee K, Allison S, Hazra R, Siberry GK, Smith R, Paul M, Van Dyke RB and Seage GR, 3rd. Sexual risk behavior among youth with perinatal HIV infection in the United States: predictors and implications for intervention development. Clin Infect Dis. 2013 Jan;56(2):283-90. PMCID: PMC3526253
• Tassiopoulos K, Bernstein J, Bernstein E. Age and sharing of needle injection equipment in a cohort of Massachusetts injection drug users: an observational study. Addict Sci Clin Pract. 2013 Dec 13;8(1):20. [Epub ahead of print] (Pub Med Journal – In Process)
• Usitalo A, Leister E, Tassiopoulos K, Allison S, Malee K, Paul ME, Smith R, Van Dyke RB, Seage GR, 3rd and Mellins CA. Relationship between viral load and self-report measures of medication adherence among youth with perinatal HIV infection. AIDS Care. AIDS Care. 2014 Jan;26(1):107-15. (Pub Med – In Process)
• Malee K, Mellins C, Huo Y, Tassiopoulos K, Smith R, Sirois P, Allison S, Kacanek D, Kapetanovic S, Williams P, Grant M, Marullo D, Aidala A, for the Pediatric HIV/AIDS Cohort Study. Prevalence, incidence and persistence of psychiatric and substance abuse disorders among mothers living with HIV. J Acquir Immune Defic Syndr 2014 (accepted).

Jennifer Schumi (2001-2006)
Current Position: Statistical Science Director, AstraZeneca

Publications while in training include:

• Schumi Jand De Gruttola V. Flexible semiparametric methods for relating patterns of multiple HIV-1 genotype mutations to phenotype responses. Antiviral Therapy, 2005; 10: S56-S56.
• Mello MM, Studdert DM, Schumi J, Brennan TA and Sage WM. Changes in physician supply and scope of practice during a malpractice crisis: Evidence from Pennsylvania. Health Affairs, 2007; 26(3): W425-W435.
• Schumi J, DiRienzo AG and DeGruttola V. Testing for associations with missing high-dimensional categorical covariates. Int J Biostat. 2008;4(1):Article 18. PMCID: PMC2835453
• Tardif JC, McMurray JJV, Klug E, Small R, Schumi J, Choi J, Cooper J, Scott R, Lewis EF, L’Allier PL and Pfeffer MA. Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. Lancet, 2008; 371(9626): 1761-1768.
• Schumi J and Wittes JT. Through the looking glass: understanding non-inferiority. Trials. 2011;12:106. PMCID: PMC3113981

Beth Ann Griffin (2001-2006)
Current Position: Biostatistician and Co-Director, RAND Center for Causal Inference, RAND Corporation

Publications while in training include:

• Griffin BAand Lagakos S. Analysis of failure time data arising from studies with alternating treatment schedules. Journal of the American Statistical Association, 2006; 101(474): 510-520.
• Grizzard TA, Bartick M, Nikolov M, Griffin BAand Lee KG. Policies and practices related to breastfeeding in Massachusetts: Hospital implementation of the ten steps to successful breastfeeding. Maternal and Child Health Journal, 2006; 10(3): 247-263.
• Griffin BA, Ramchand R, Harris K, McCaffrey D and Morral A. Smoking rates among adolescents in substance abuse treatment programs. Psychiatric Services, 2007; 58(12): 1528-1528.
• Lara-Cinisomo S and Griffin BA. Factors associated with major depression among mothers in Los Angeles. Womens Health Issues, 2007; 17(5): 316-324.
• McCaffrey DF, Morral AR, Ridgeway G and Griffin BA. Interpreting treatment effects when cases are institutionalized after treatment. Drug and Alcohol Dependence, 2007; 89(2-3): 126-138.
• Griffin BAand Lagakos SW. Design and analysis of arm-in-cage experiments: Inference for three-state progressive disease models with common periodic observation times. Biometrics, 2008; 64(2): 337-344.
• Harris KM, Griffin BA, McCaffrey DF and Morral AR. Inconsistencies in self-reported drug use by adolescents in substance abuse treatment: Implications for outcome and performance measurements. Journal of Substance Abuse Treatment, 2008; 34(3): 347-355.
• Ramchand R, Griffin BA, Harris KM, McCaffrey DF and Morral AR. A prospective investigation of suicide ideation, attempts, and use of mental health service among adolescents in substance abuse treatment. Psychol Addict Behav. 2008 Dec;22(4):524-32. PMCID: PMC2766662
• Griffin BA, Elliott MN, Coleman AL and Cheng EM. Incorporating mortality risk into estimates of 5-year glaucoma risk. Am J Ophthalmol. 2009 Dec;148(6):925-31 e7. PMCID: PMC2830147
• Griffin BA, Jain AK, Davies-Cole J, Glymph C, Lum G, Washington SC and Stoto MA. Early detection of influenza outbreaks using the DC Department of Health’s syndromic surveillance system. BMC Public Health. 2009;9:483. PMCID: PMC2807869

Kunjal Patel (2001-2006)
Current Position: Senior Research Scientist, Department of Epidemiology, Harvard T. H. Chan School of Public Health

Publications while in training include:

• Patel K, Weinberg GA, Buchacz K, McIntosh K, Dankner WM and Seage GR. Simple pediatric AIDS severity score (PASS) – A pediatric severity score for resource-limited settings. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 2006; 43(5): 611-617.
• Seage GR, Buchacz K, Weinberg GA, Patel K, McIntosh K and Dankner WM. The pediatric AIDS severity score (PASS) – A multidimensional AIDS-severity adjustment for pediatric HIV infection. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 2006; 43(5): 603-610.
• Patel K, Hernan MA, Williams PL, Seeger JD, McIntosh K, Van Dyke RB and Seage GR. Long-term effects of highly active antiretroviral therapy on CD4(+) cell evolution among children and adolescents infected with HIV: 5 years and counting. Clinical Infectious Diseases, 2008; 46(11): 1751-1760.
• Patel K, Hernan MA, Williams PL, Seeger JD, McIntosh K, Van Dyke RB and Seage GR. Long-term effectiveness of highly active Antiretroviral therapy on the survival of children and adolescents with HIV infection: A 10-year follow-up study. Clinical Infectious Diseases, 2008; 46(4): 507-515.
• Patel K, Shapiro DE, Brogly SB, Livingston EG, Stek AM, Bardeguez AD, Tuomala RE for the P1025 team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group. Prenatal protease inhibitor use and risk of preterm birth among HIV-infected women initiating antiretroviral drugs during pregnancy. J Infect Dis. 2010; 201:1035-44. PMCID: PMC294635
• Livingston EG, Huo Y, Patel K, Brogly SB, Tuomala R, Scott GB, Bardeguez A, Stek A, Read JS; International Maternal Pediatric Adolescent AIDS Clinical Trials Group Protocol 1025 Study Team. Mode of delivery and infant respiratory morbidity among infants born to HIV-1-infected women. Obstet Gynecol. 2010; 116:335-43. PMCID: PMC2964131
• Van Dyke RB, Patel K, Siberry GK, Burchett SK, Spector SA, Chernoff MC, Read JS, Mofenson LM, Seage GR 3rd; Pediatric HIV/AIDS Cohort Study. Antiretroviral treatment of US children with perinatally acquired HIV infection: temporal changes in therapy between 1991 and 2009 and predictors of immunologic and virologic outcomes. JAIDS. 2011;57:165-73. PMCID: PMC3125481
• Siberry GK, Patel K, Van Dyke RB, Hazra R, Burchett SK, Spector SA, Paul ME, Read JS, Wiznia A, Seage GR 3rd; for the Pediatric HIV/AIDS Cohort Study(PHACS). CD4+ Lymphocyte-Based Immunologic Outcomes of Perinatally HIV-Infected Children During Antiretroviral Therapy Interruption. J Acquir Immune Defic Syndr. 2011;57:223-9. PMCID: PMC3156860
• Geffner ME, Patel K, Miller TL, Hazra R, Silio M, Van Dyke RB, Borkowsky W, Worrell C, DiMeglio LA, Jacobson DL; for the Pediatric HIV/AIDS Cohort Study. Factors Associated with Insulin Resistance among Children and Adolescents Perinatally-Infected with HIV-1 in the Pediatric HIV/AIDS Cohort Study (PHACS). Horm Res Paediatr. 2011;76:386-91. PMCID:PMC3697231
• Jacobson DL, Patel K, Siberry GK, Van Dyke R, DiMeglio LA, Geffner M, Chen JS, McFarland E, Borkowsky W , Silio M, Fielding RA, Siminski S, and Miller TL; for the Pediatric HIV/AIDS Cohort Study. Body fat distribution in perinatally HIV-infected and HIV-exposed but uninfected children in the era of highly active antiretroviral therapy: Outcomes from the Pediatric HIV/AIDS Cohort Study (PHACS). Am J Clin Nutr. 2011;94:1485-95. PMCID: PMC3252548
• Miller TL, Borkowsky W , DiMeglio LA, Dooley L, Geffner M, Hazra R, McFarland E, Mendez AJ, Patel K, Siberry GK, VanDyke RB, Worrell CJ, and Jacobson DL; for the Pediatric HIV/AIDS Cohort Study. Metabolic Abnormalities and Viral Replication are Associated with Biomarkers of Vascular Dysfunction in HIV-Infected Children. HIV Med. 2012;13:264-75. PMCID: PMC3297698
• Patel K, van Dyke RB, Mittleman MA, Colan SD, Oleske JM, Seage GR 3rd; for the International Maternal Pediatric Adolescent AIDS Clinical Trials 219219C Study Team. The Impact of HAART on Cardiomyopathy among Children and Adolescents Perinatally Infected with HIV-1. AIDS. 2012;26:2027-37. PMCID: PMC3513344
• Purswani M, Patel K, Kopp JB, Seage III GR, Chernoff MC, Hazra R, Siberry GK, Mofenson LM, Scott GB, Van Dyke RB, for the Pediatric HIV/AIDS Cohort Study. Tenofovir treatment duration predicts proteinuria in a multi-ethnic United States cohort of children and adolescents with perinatal HIV-1 infection. Pediatr Infect Dis J. 2013;32:495-500. PMCID: PMC3800277
• Read JS, Huo Y, Patel K, Mitchell M, Scott GB. Laboratory Abnormalities Among HIV-Exposed, Uninfected Infants: IMPAACT Protocol P1025. J Pediatric Infect Dis Soc. 2012 Jun;1(2):92-102. Epub 2012 May 3. PMCID:PMC3656554

Jovanna R. Baptista (2000-2002)
Current Position: Director Biometrics, Shire Pharmaceuticals

Publications while in training include:

• Kiryu S, Raptopoulos V, Baptista Jand Hatabu H. Increased prevalence of coronary artery calcification in patients with suspected pulmonary embolism. Academic Radiology, 2003; 10(8): 840-845.
• Raptopoulos V, Kiryu S, Siewert B, Baptista J, McNamara A and Rosen M. Coronary calcium scoring with low-dose non-gated MDCT of the chest. American Journal of Roentgenology, 2004; 182(4): 39-39.
• Gaston SM, Soares MA, Siddiqui MM, Vu D, Lee JM, Goldner DL, Brice MJ, Shih JC, Upton MP, Perides G, Baptista J, Lavin PT, Bloch BN, Genega EM, Rubin MA and Lenkinski RE. Tissue-print and print-phoresis as platform technologies for the molecular analysis of human surgical specimens: mapping tumor invasion of the prostate capsule. Nature Medicine, 2005; 11(1): 95-101.
• Pedrosa I, Morrin M, Oleaga L, Baptista Jand Rofsky NM. Is true FISP imaging reliable in the evaluation of venous thrombosis? American Journal of Roentgenology, 2005; 185(6): 1632-1640.
• Singh A, Hertel J, Bernardo M, Baptista J, Kausz A, Brenner L and Pereira B. A double-blind, placebo-controlled, randomized phase III study of the safety of ferumoxytol as a new intravenous iron replacement therapy. American Journal of Kidney Diseases, 2007; 49(4): A32-A32.
• Zamboni GA, Kruskal JB, Vollmer CM, Baptista J, Callery MP and Raptopoulos VD. Pancreatic adenocarcinoma: Value of multidetector CT angiography in preoperative evaluation. Radiology, 2007; 245(3): 770-778.

Dionne Alicbusan Graham (1998-2002)
Current Position: Senior Biostatistician / Assistant Professor of Pediatrics Children’s Hospital Boston/Harvard Medical School

Publications while in training include:

• Costello JM, Graham DA, Morrow DF, Poner-Bynoe G, Sandora TJ and Laussen PC. Risk factors for central line-associated bloodstream infection in a pediatric cardiac intensive care unit. Critical Care Medicine, 2007; 35(12): A262-A262.
• Costello JM, Morrow DF, Graham DA, Potter-Bynoe G, Sandora TJ and Laussen PC. Systematic intervention to reduce central line-associated bloodstream infection rates in a pediatric cardiac intensive care unit. Pediatrics, 2008; 121(5): 915-923.
• Mooij CF, de Wit CJ, Graham DA, Powell AJ and Geva T. Reproducibility of MRI measurements of right ventricular size and function in patients with normal and dilated ventricles. Journal of Magnetic Resonance Imaging, 2008; 28(1): 67-73.
• Soriano BD, Hoch M, Ithuralde A, Geva T, Powell AJ, Kussman BD, Graham DA, Tworetzky W and Marx GR. Matrix-array 3-dimensional echocardiographic assessment of volumes, mass, and ejection fraction in young pediatric patients with a functional single ventricle – A comparison study with cardiac magnetic resonance. Circulation, 2008; 117(14): 1842-1848.
• Tierney ESS, Graham DA, McElhinney DB, Trevey S, Freed MD, Colan SD and Geva T. Echocardiographic predictors of mitral stenosis-related death or intervention in infants. American Heart Journal, 2008; 156(2): 384-390.

Lisa Carol Miller Wruck (1999-2005)
Current Position: Director, Duke Clinical Research Institute, Center for Predictive Medicine

Publications while in training include:

• Travison TG, Araujo AB, Wruck LM, Kupelian V, O’Donnell AB and McKinlay JB. Assessment of screening evaluations is not straightforward Comment on: “Comparison of screening questionnaires for the diagnosis of hypogonadism” [J.E. Morley, H.M. Perry III, R.T. Kevorkian, P. Patrick, Maturitas 53 (2006) 424-429]. Maturitas, 2006; 54(3): 305-6; author reply 307-8.
• Wruck LM, Yiannoutsos CT and Hughes MD. A sequential design to estimate sensitivity and specificity of a diagnostic or screening test. Statistics in Medicine, 2006; 25(20): 3458-3473.
• Albo M, Wruck L, Baker J, Brubaker L, Chai T, Dandreo KJ, Diokno A, Goode P, Kraus S, Kusek JW, Lemack G, Lowder J and Steers W. The relationships among measures of incontinence severity in women undergoing surgery for stress urinary incontinence. J Urol, 2007; 177(5): 1810-4.
• Lacro RV, Dietz HC, Wruck LM, Bradley TJ, Colan SD, Devereux RB, Klein GL, Li JS, Minich LL, Paridon SM, Pearson GD, Printz BF, Pyeritz RE, Radojewski E, Roman MJ, Saul JP, Stylianou MP and Mahony L. Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome. American Heart Journal, 2007; 154(4): 624-631.
• Lacro RV, Dietz HC, Wruck LM, Bradley TJ, Colan SD, Devereux RB, Klein GL, Li JS, Minich LL, Paridon SM, Pearson GD, Printz BF, Pyeritz RE, Radojewski E, Roman MJ, Saul JP, Stylianou MP, Mahony L and Pediat Heart Network I. Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome. American Heart Journal, 2007; 154: 624-631.
• Nager CW, Albo ME, Fitzgerald MP, McDermott S, Wruck L, Kraus S, Howden N, Norton P, Sirls L, Varner E and Zimmern P. Reference urodynamic values for stress incontinent women. Neurourol Urodyn, 2007; 26(3): 333-40.
• Pocock SJ, Travison TG and Wruck LM. Figures in clinical trial reports: current practice & scope for improvement. Trials, 2007; 8: 36.
• Pocock SJ, Travison TG and Wruck LM. How to interpret figures in reports of clinical trials. British Medical Journal, 2008; 336(7654): 1166-1169.

Meredith Goldwasser (1999-2005)
Current Position: Senior Director, Head of Biometrics & Data Management, Agios Pharmaceuticals, Inc.

Publications while in training include:

• Goldwasser MAand Hughes MD. Semi-parametric quantile regression for longitudinal analysis in the presence of missing at random data. Controlled Clinical Trials, 2003; 24: 64S-65S.
• Goldwasser MA, Tian L and Wei LJ. Statistical inference for infinite-dimensional parameters via asymptotically pivotal estimating functions. Biometrika, 2004; 91(1): 81-94.
• Li AH, Rue M, Zhou JB, Wang HJ, Goldwasser MA, Neuberg D, Dalton V, Zuckerman D, Lyons C, Silverman LB, Sallan SE, Gribben JG and Dana-Farber Cancer I. Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis. Blood, 2004; 103(12): 4602-4609.
• Li AH, Zhou JB, Wang HJ, Goldwasser MA, Lyons C, Sallan SE, Silverman LB and Gribben JG. Molecular analysis of T-cell receptor gene rearrangements in children with T-cell acute lymphoblast leukemia on DFCI ALL consortium protocol 95-01. Blood, 2004; 104(11): 308A-308A.
• Waber DP, Silverman LB, Catania L, Mautz W, Rue M, Gelber RD, Levy DE, Goldwasser MA, Adams H, Dufresne A, Metzger V, Romero I, Tarbell NJ, Dalton VK and Sallan SE. Outcomes of a randomized trial of hyperfractionated cranial radiation therapy for treatment of high-risk acute lymphoblastic leukemia: Therapeutic efficacy and neurotoxicity. Journal of Clinical Oncology, 2004; 22(13): 2701-2707.
• Zhou JB, Li AH, Goldwasser MA, Wang HJ, Dalton V, Lyons C, McBride KD, Sallan SE, Silverman LB and Gribben JG. Quantitative analysis of minimal residual disease at the completion of induction therapy predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL consortium protocol 95-01. Blood, 2004; 104(11): 96A-96A.
• Argiris A, Goldwasser MA, Brockstein B, Axelrod R and Forastiere A. Weekly docetaxel (D) and irinotecan (I) in patients (pts) with recurrent or metastatic head and neck cancer (HNC): A phase II trial of the Eastern Cooperative Oncology Group (ECOG). Journal of Clinical Oncology, 2005; 23(16): 507S-507S.
• Burtness B, Goldwasser MA, Flood W, Mattar B and Forastiere AA. Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: An eastern cooperative oncology group study. Journal of Clinical Oncology, 2005; 23(34): 8646-8654.
• Li AH, Goldwasser MA, Zhou JB, Armstrong SA, Wang H, Dalton V, Fletcher JA, Sallan SE, Silverman LB and Gribben JG. Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias. British Journal of Haematology, 2005; 131(2): 185-192.
• Argiris A, Goldwasser MA, Burtness B, Deconti R, Axelrod R, Van Waes C and Forastiere A. A phase II trial of PS-341 (bortezomib) followed by the addition of doxorubicin at progression in incurable adenoid cystic carcinoma of the head and neck: An Eastern Cooperative Oncology Group study. Journal of Clinical Oncology, 2006; 24(18): 298S-298S.
• Barry E, Levy DE, Goldwasser MA, Loh ML, Deangelo DJ, Sallan SE and Silverman LB. Outcome of adolescents with acute lymphoblastic leukemia (ALL) treated on Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocols, 1991-2000. Journal of Clinical Oncology, 2006; 24(18): 507S-507S.
• Burtness B, Goldwasser MA, Axelrod R, Argiris A and Forastiere AA. A randomized phase II study of BMS-247550 (ixabepilone) given daily x 5 days every 3 weeks or weekly in patients with metastatic or recurrent squamous cell cancer of the head and neck. Journal of Clinical Oncology, 2006; 24(18): 288S-288S.
• Loh ML, Goldwasser MA, Silverman LB, Poon WM, Vattikuti S, Cardoso A, Neuberg DS, Shannon KM, Sallan SE and Gilliland DG. Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute consortium protocol 95-01. Blood, 2006; 107(11): 4508-4513.
• Poeta LM, Goldwasser MA, Forastiere A, Benoit N, Califano J, Ridge JA, Goodwin J, Kenady D, Sidransky D and Koch WM. Prognostic implication of p53 mutations in HNSCC: Results of intragroup margin study (E4393). Journal of Clinical Oncology, 2006; 24(18): 281S-281S.
• Baxter NN, Goldwasser MA, Paszat L, Saskin R, Urbach DR and Rabeneck L. A population-based case control study of the effectiveness of colonoscopy for prevention of death from CRC. Gastroenterology, 2007; 132(4): A88-A88.
• Cmelak AJ, Li SG, Goldwasser MA, Murphy B, Cannon M, Pinto H, Rosenthal DI, Gillison M and Forastiere AA. Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cell carcinomas of the larynx or oropharynx: Results of Eastern Cooperative Oncology Group study E2399. Journal of Clinical Oncology, 2007; 25(25): 3971-3977.
• Poeta ML, Manola J, Goldwasser MA, Forastiere A, Benoit N, Califano JA, Ridge JA, Goodwin J, Kenady D, Saunders J, Westra W, Sidransky D and Koch WM. TP53 mutations and survival in squamous-cell carcinoma of the head and neck. New England Journal of Medicine, 2007; 357(25): 2552-2561.
• Rabeneck L, Paszat L, Hilsden RJ, Saskin R, Leddin D, Grunfeld E, Wai E, Goldwasser MAand Stukel T. Risks of serious complications of colonoscopy among four Canadian provinces: A population-based cohort study. Gastroenterology, 2007; 132(4): A88-A88.
• Tinmouth JM, Cooper MA, Stafford SE, Goldwasser MA, Moineddin R, Richardson BJ, Stal JM, Habal F, Kortan PP, Yong E, Chen GI, Hsieh E, Paszat L and Rabeneck L. Evaluating quality indicators for screening colonscopy: Withdrawal time and prior advanced neoplasia detection rates, measured relative to expected rates, are not associated with detection of advanced neoplasia. Gastrointestinal Endoscopy, 2007; 65(5): AB264-AB264.
• Austin PC and Goldwasser MA. Pisces did not have increased heart failure: data-driven comparisons of binary proportions between levels of a categorical variable can result in incorrect statistical significance levels. Journal of Clinical Epidemiology, 2008; 61: 295-300.
• Rabeneck L, Paszat L, Hilsden RJ, Saskin R, Leddin D, Grunfeld E, Wai ES, Goldwasser MAand Stukel TA. Factors associated with risk of serious complications of colonoscopy: A population-based study. Gastroenterology, 2008; 134(4): A88-A88.

Nuala McGrath (1998-2002)
Current Position: Professor of Epidemiology and Sexual Health, Department of Medicine, University of Southampton

Publications while in training include:

• Spector SA, Gelber RD, McGrath N, et al. Controlled Trial of Intravenous Immune Globulin for the Prevention of Serious Bacterial-Infections in Children Receiving Zidovudine for Advanced Human-Immunodeficiency-Virus Infection. New England Journal of Medicine, 1994; 331(18): 1181-1187.
• Brady MT, McGrath N, Brouwers P, Gelber R, et al. Randomized study of the tolerance and efficacy of high- versus low-dose zidovudine in human immunodeficiency virus-infected children with mild to moderate symptoms (AIDS Clinical Trials Group 128). Journal of Infectious Diseases, 1996; 173(5): 1097-1106.
• Fawzi WW, Msamanga GI, Spiegelman D, Urassa EJN, McGrath N, Mwakagile D, Antelman G, Mbise R, Herrera G, Kapiga S, Willett W and Hunter DJ. Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania. Lancet, 1998; 351(9114): 1477-1482.
• Lindsey JC and McGrath NM. Interpreting treatment differences when patients drop out of a clinical trial. AIDS Patient Care and Stds, 1998; 12(4): 275-285.
• McSherry GD, Shapiro DE, Coombs RW, McGrath N, Frenkel LM, Britto P, Culnane M and Sperling RS. The effects of zidovudine in the subset of infants infected with human immunodeficiency virus type-1 (Pediatric AIDS Clinical Trials Group Protocol 076). Journal of Pediatrics, 1999; 134(6): 717-724.
• Pearson DA, McGrath NM, Nozyce M, Nichols SL, Raskino C, Brouwers P, Lifschitz MC, Baker CJ and Englund JA. Predicting HIV disease progression in children using measures of neuropsychological and neurological functioning. Pediatrics, 2000; 106(6).
• Hosegood V, McGrath N, Herbst K and Timaeus IM. The impact of adult mortality on household dissolution and migration in rural South Africa. AIDS, 2004; 18(11): 1585-1590.
• Dabis F, Leroy V, Newell ML, Read JS, Coutsoudis A, Dabis F, Fawzi W,…, McGrath N, et al. Mortality among HIV-1-infected women according to children’s feeding modality – An individual patient data meta-analysis. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 2005; 39(4): 430-438.
• McGrath N, Bellinger D, Robins J, Msamanga GI, Tronick E and Fawzi WW. Effect of maternal multivitamin supplementation on the mental and psychomotor development of children who are born to HIV-1 – Infected mothers in Tanzania. Pediatrics, 2006; 117(2): E216-E225.
• McGrath N, Fawzi WW, Bellinger D, Robins J, Msamanga GI, Manji K and Tronick E. Timing of mother-to-child transmission of human immunodeficiency virus infection and neurodevelopment of children in Tanzania. Pediatric Infectious Disease Journal, 2006; 25(1): 47-52.
• Hosegood V, Floyd S, Marston M, Hill C, McGrath N, Isingo R, Crampin A and Zaba B. The effects of high HIV prevalence on orphanhood and living arrangements of children in Malawi, Tanzania, and South Africa. Population Studies-a Journal of Demography, 2007; 61(3): 327-336.
• Jahn A, Crampin AC, Glynn JR, Mwinuka V, Mwaiyeghele E, Mwafilaso J, Branson K, McGrath N, Fine PEM and Zaba B. Evaluation of a village-informant driven demographic surveillance system in Karonga, Northern Malawi. Demographic Research, 2007; 16: 219-247.
• McGrath N, Kranzer K, Saul J, Crampin AC, Malema S, Kachiwanda L, Zaba B, Jahn A, Fine PEM and Glynn JR. Estimating the need for antiretroviral treatment and an assessment of a simplified HIV/AIDS case definition in rural Malawi. AIDS, 2007; 21: S105-S113.
• McGrath NMand Cooke GS. Frequency of and risk factors for HIV dementia in an HIV clinic in sub-saharan Africa. Neurology, 2007; 69(4): 411-412.
• Moultrie TA and McGrath N. Teenage fertility rates falling in South Africa. Samj South African Medical Journal, 2007; 97(6): 442-443.
• Ndinda C, Chimbwete C, McGrath Nand Pool R. Community attitudes towards individuals living with HIV in rural KwaZulu-Natal, South Africa. AIDS Care-Psychological and Socio-Medical Aspects of AIDS/HIV, 2007; 19(1): 92-101.
• White RG, Vynnycky E, Glynn JR, Crampin AC, Jahn A, Mwaungulu F, Mwanyongo O, Jabu H, Phir H, McGrath N, Zaba B and Fine PEM. HIV epidemic trend and antiretroviral treatment need in Karonga District, Malawi. Epidemiology and Infection, 2007; 135(6): 922-932.
• Jahn A, Floyd S, Crampin AC, Mwaungulu F, Mvula H, Munthali F, McGrath N, Mwafilaso J, Mwinuka V, Mangongo B, Fine PEM, Zaba B and Glynn JR. Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in Malawi. Lancet, 2008; 371(9624): 1603-1611.
• Jahn A, Floyd S, Mwinuka V, Mwafilaso J, Mwagomba D, Mkisi RE, Katsulukuta A, Khunga A, Crampin AC, Branson K, McGrath Nand Fine PEM. Ascertainment of childhood vaccination histories in northern Malawi. Tropical Medicine & International Health, 2008; 13(1): 129-138.
• Moultrie TA, Hosegood V, McGrath N, Hill C, Herbst K and Newell ML. Refining the criteria for stalled fertility declines: An application to rural KwaZulu-Natal, South Africa, 1990-2005. Studies in Family Planning, 2008; 39(1): 39-48.
• Ndinda C, Chimbwete C, McGrath Nand Pool R. Perceptions of anal sex in rural South Africa. Culture Health & Sexuality, 2008; 10(2): 205-212.

Elizabeth Renata Brown (1998-2002)
Current Position: Research Professor, Department of Biostatistics, University of Washington

Publications while in training include:

• McCloskey L, Plough AL, Power KL, Higgins CA, Cruz AN and Brown ER. A community-wide infant mortality review: Findings and implications. Public Health Reports, 1999; 114(2): 165-177.
• Brown ER, MaWhinney S, Jones RH, Kafadar K and Young B. Improving the fit of bivariate smoothing splines when estimating longitudinal immunological and virological markers in HIV patients with individual antiretroviral treatment strategies. Statistics in Medicine, 2001; 20(16): 2489-2504.
• Brown ERand Ibrahim JG. Bayesian approaches to joint cure-rate and longitudinal models with applications to cancer vaccine trials. Biometrics, 2003; 59(3): 686-693.
• Brown ERand Ibrahim JG. A Bayesian semiparametric joint hierarchical model for longitudinal and survival data. Biometrics, 2003; 59(2): 221-228.
• Jenny NS, Brown ER, Detrano R, Folsom AR, Herrington D, Jacobs D, Manolio TA and Tracy RP. Race/ethnic differences in the relationship of inflammatory markers to coronary calcium. Circulation, 2003; 108(17): 753-753.
• Eshleman SH, Guay LA, Mwatha A, Brown ER, Cunningham SP, Musoke P, Mmiro F and Jackson JB. Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine (HIVNET 012). JAIDS-Journal of Acquired Immune Deficiency Syndromes, 2004; 35(2): 126-130.
• Eshleman SH, Guay LA, Mwatha A, Cunningham SP, Brown ER, Musoke P, Mmiro F and Jackson JB. Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose NVP prophylaxis: HIVNET 012. AIDS Research and Human Retroviruses, 2004; 20(6): 595-599.
• Eshleman SH, Wang J, Guay LA, Cunningham SP, Mwatha A, Brown ER, Musoke P, Mmiro F and Jackson JB. Distinct patterns of selection and fading of K103N and Y181C are seen in women with subtype A vs D HIV-1 after single dose nevirapine: HIVNET 012. Antiviral Therapy, 2004; 9(4): U54-U54.
• Horton NJ, Brown ERand Qian LJ. Use of R as a toolbox for mathematical statistics exploration. American Statistician, 2004; 58(4): 343-357.
• Brown ER, Ibrahim JG and DeGruttola V. A flexible B-spline model for multiple longitudinal biomarkers and survival. Biometrics, 2005; 61(1): 64-73.
• Chi BH, Wang L, Read JS, Sheriff M, Fiscus S, Brown ER, Taha TE, Valentine M and Goldenberg R. Timing of maternal and neonatal dosing of nevirapine and the risk of mother-to-child transmission of HIV-1: HIVNET 024. AIDS, 2005; 19(16): 1857-1864.
• Eshleman SH, Guay LA, Wang J, Mwatha A, Brown ER, Musoke P, Mmiro F and Jackson JB. Distinct patterns of emergence and fading of K103N and Y181C in women with subtype A vs. D after single-dose nevirapine – HIVNET 012. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 2005; 40(1): 24-29.
• Goldenberg RL, Mudenda V, Read JS, Brown ER, Sinkala M, Kamiza S, Martinson F, Kaaya E, Hoffman I, Fawzi W, Valentine M and Taha TE. HPTN 024 study: Histologic chorioamnionitis, antibiotics and adverse infant outcomes in a predominantly HIV-1-infected African population. American Journal of Obstetrics and Gynecology, 2006; 195(4): 1065-1074.
• Taha TE, Brown ER, Hoffman IF, Fawzi W, Read JS, Sinkala M, Martinson FEA, Kafulafula G, Msamanga G, Emel L, Adeniyi-Jones S and Goldenberg R. A phase III clinical trial of antibiotics to reduce chorioamnionitis-related perinatal HIV-1 transmission. AIDS, 2006; 20(9): 1313-1321.
• Chi BH, Wang L, Read JS, Taha TE, Sinkala M, Brown ER, Valentine M, Martinson F and Goldenberg RL. Predictors of stillbirth in sub-saharan Africa. Obstetrics and Gynecology, 2007; 110(5): 989-997.
• Goldenberg RL, Andrews WW, Hoffman I, Fawzi W, Valentine M, Young A, Read JS, Brown ER, Mudenda V, Kafulafula G, Mwinga K and Taha TE. Fetal fibronectin and adverse infant outcomes in a predominantly human immunodeficiency virus-infected African population – A randomized controlled trial. Obstetrics and Gynecology, 2007; 109(2): 392-401.